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Allopurinol hypersensitivity syndrome (AHS) typically occurs in persons with preexisting kidney failure. [3]: 119 Weeks to months after allopurinol is begun, the patient develops a morbilliform eruption [3]: 119 or, less commonly, develops one of the far more serious and potentially lethal severe cutaneous adverse reactions viz., the DRESS syndrome, Stevens Johnson syndrome, or toxic epidermal ...
Allopurinol is used to reduce urate formation in conditions where urate deposition has already occurred or is predictable. The specific diseases and conditions where it is used include gouty arthritis, skin tophi, kidney stones, idiopathic gout; uric acid lithiasis; acute uric acid nephropathy; neoplastic disease and myeloproliferative disease with high cell turnover rates, in which high urate ...
Most chapters within a unit are organized as follows, although there are some exceptions. Nursing-sensitive patient outcomes (NOC) are discussed before interventions. This is because in the sequence of clinical reasoning desired outcomes are identified prior to selection of interventions to achieve the outcomes.
Patient safety is a discipline focused on improving health care through the prevention, reduction, reporting, and analysis of errors and other types of unnecessary harm that often lead to adverse patient events.
The symptoms of DRESS syndrome usually begin 2 to 6 weeks but uncommonly up to 8–16 weeks after exposure to an offending drug. Symptoms generally include fever, an often itchy rash which may be morbilliform or consist mainly of macules or plaques, facial edema (i.e. swelling, which is a hallmark of the disease), enlarged and sometimes painful lymph nodes, and other symptoms due to ...
The second two levels form a taxonomy in which each intervention is grouped into 27 classes, and each class is grouped into six domains. An intent of this structure is to make it easier for a nurse to select an intervention for the situation, and to use a computer to describe the intervention in terms of standardized labels for classes and domains.
The group exposed to treatment (left) has the risk of an adverse outcome (black) reduced by 50% (RRR = 0.5) compared to the unexposed group (right). In epidemiology , the relative risk reduction (RRR) or efficacy is the relative decrease in the risk of an adverse event in the exposed group compared to an unexposed group.
Supervised injection sites are also known as overdose prevention centers (OPCs), [6] supervised injection facilities, [7] safe consumption rooms, [8] safe injection sites, [1] safe injection rooms, [9] fix rooms, [10] fixing rooms, [11] safer injection facilities (SIF), drug consumption facilities (DCF), [2] drug consumption rooms (DCRs), [12] medically supervised injecting centres (MSICs) and ...