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The primary infection is most commonly caused by bacteria, but also may be by fungi, viruses or parasites. It may be located in any part of the body, but most commonly in the lungs, brain, urinary tract, skin or abdominal organs. [2] It can cause multiple organ dysfunction syndrome (formerly known as multiple organ failure) and death. [3]
It is the second-leading cause of death in non-coronary intensive care unit (ICU) and the tenth-most-common cause of death overall (the first being heart disease). [111] Children under 12 months of age and elderly people have the highest incidence of severe sepsis. [ 30 ]
Brain death is used as an indicator of legal death in many jurisdictions, [7] but it is defined inconsistently and often confused by the public. [8] Various parts of the brain may keep functioning when others do not anymore, and the term "brain death" has been used to refer to various combinations.
A concussion, also known as a mild traumatic brain injury (mTBI), is a head injury that temporarily affects brain functioning. [8] Symptoms may include headache, dizziness, difficulty with thinking and concentration, sleep disturbances, mood changes, a brief period of memory loss, brief loss of consciousness; problems with balance; nausea; blurred vision; and mood changes.
Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
Brain: Cerebral infarction is the ischemic kind of stroke due to a disturbance in the blood vessels supplying blood to the brain. It can be atherothrombotic or embolic. [ 9 ] Stroke caused by cerebral infarction should be distinguished from two other kinds of stroke: cerebral hemorrhage and subarachnoid hemorrhage .
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Encephalitis with meningitis is known as meningoencephalitis, while encephalitis with involvement of the spinal cord is known as encephalomyelitis. [2] The word is from Ancient Greek ἐγκέφαλος, enképhalos 'brain', [37] composed of ἐν, en, 'in' and κεφαλή, kephalé, 'head', and the medical suffix -itis 'inflammation'. [38]