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2. We Found Deals on Hoka, Nike, and Adidas Running Sneakers - AOL

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   Our commerce editors spent more than five hours combing the internet to find a boatload of great discounted sneakers to shop for Black Friday and Cyber Monday.

3. Endomorphin-2 - Wikipedia

   en.wikipedia.org/wiki/Endomorphin-2

   Endomorphin-2 (EM-2) is an endogenous opioid peptide and one of the two endomorphins. [1] It has the amino acid sequence Tyr-Pro-Phe-Phe-NH 2.It is a high affinity, highly selective agonist of the μ-opioid receptor, and along with endomorphin-1 (EM-1), has been proposed to be the actual endogenous ligand of this receptor (that is, rather than the endorphins).

4. Endomorphin - Wikipedia

   en.wikipedia.org/wiki/Endomorphin

   Alternately, endomorphin-2 is predominantly found in the spinal cord, specifically in presynaptic terminals of afferent neurons in the dorsal horn region. It has been found co-localized with calcitonin as well as the pain-conveying neurotransmitter, substance P. Neither endomorphin-1 or 2 have been identified in the amygdala or the hippocampus. [2]

5. Enkephalin - Wikipedia

   en.wikipedia.org/wiki/Enkephalin

   There are three well-characterized families of opioid peptides produced by the body: enkephalins, β-endorphin, and dynorphins.The met-enkephalin peptide sequence is coded for by the enkephalin gene; the leu-enkephalin peptide sequence is coded for by both the enkephalin gene and the dynorphin gene. [3]

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7. We Can't Believe the Asics Gel-Kayano 29 Is 50% Off Right Now

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8. FDA approves new pain medication as an alternative to opioids ...

   www.aol.com/news/fda-approves-pain-medication...

   The FDA on Thursday approved a new class of pain medication that provides an alternative to opioids. It will be sold under the brand name Journavx.

9. Neoendorphin - Wikipedia

   en.wikipedia.org/wiki/Neoendorphin

   The α-neoendorphin is present in greater amounts in the brain than β-neoendorphin. Both are products of the dynorphin gene, which also expresses dynorphin A, dynorphin A-(1-8), and dynorphin B. [2] These opioid neurotransmitters are especially active in Central Nervous System receptors, whose primary function is pain sensation. [3]