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  2. Hepatic portal system - Wikipedia

    en.wikipedia.org/wiki/Hepatic_portal_system

    Hepatic portal vein; Splenic vein; Superior mesenteric vein; Inferior mesenteric vein; The superior mesenteric vein and the splenic vein come together to form the actual hepatic portal vein. The inferior mesenteric vein connects in the majority of people on the splenic vein, but in some people, it is known to connect on the portal vein or the ...

  3. Portal vein - Wikipedia

    en.wikipedia.org/wiki/Portal_vein

    The portal vein and hepatic arteries form the liver's dual blood supply. Approximately 75% of hepatic blood flow is derived from the portal vein, while the remainder is from the hepatic arteries. [4] Unlike most veins, the portal vein does not drain into the heart.

  4. Lobules of liver - Wikipedia

    en.wikipedia.org/wiki/Lobules_of_liver

    In histology (microscopic anatomy), the lobules of liver, or hepatic lobules, are small divisions of the liver defined at the microscopic scale. The hepatic lobule is a building block of the liver tissue, consisting of portal triads, hepatocytes arranged in linear cords between a capillary network, and a central vein.

  5. Transjugular intrahepatic portosystemic shunt - Wikipedia

    en.wikipedia.org/wiki/Transjugular_intrahepatic...

    By creating a shunt from the portal vein to the hepatic vein, this intervention allows portal blood an alternative avenue for draining into systemic circulation. In bypassing the flow-resistant liver, the net result is a reduced pressure drop across the liver and a decreased portal venous pressure. Decreased portal venous pressure in turn ...

  6. Portal venous system - Wikipedia

    en.wikipedia.org/wiki/Portal_venous_system

    The human hepatic portal system delivers about three-fourths of the blood going to the liver.The final common pathway for transport of venous blood from spleen, pancreas, gallbladder and the abdominal portion of the gastrointestinal tract [2] (with the exception of the inferior part of the anal canal and sigmoid colon) is through the hepatic portal vein.

  7. First pass effect - Wikipedia

    en.wikipedia.org/wiki/First_pass_effect

    Illustration showing the hepatic portal vein system. The first pass effect (also known as first-pass metabolism or presystemic metabolism) is a phenomenon of drug metabolism at a specific location in the body which leads to a reduction in the concentration of the active drug before it reaches the site of action or systemic circulation.

  8. Porta hepatis - Wikipedia

    en.wikipedia.org/wiki/Porta_hepatis

    The hepatic duct lies in front and to the right, the hepatic artery to the left, and the portal vein behind and between the duct and artery. It also transmits nerves and lymphatics . Sympathetic nerves - these provide afferent pain impulses from the liver and gall bladder to the brain.

  9. Hepatic veins - Wikipedia

    en.wikipedia.org/wiki/Hepatic_veins

    The right hepatic vein is the longest and largest of all the hepatic veins. It drains the liver segments VI and VII in their entirety, and variably participates in the drainage of segments V and VIII; the extent of drainage of the latter two segments by the right hepatic veins as opposed to the middle hepatic vein and possible variant accessory veins determines the calibre of the right hepatic ...