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Phosphate supplementation is often required in people who have undergone surgery and in chronically malnourished people. [1] Sodium phosphate and potassium phosphate can be administered intravenously or orally. Tablets combining the forms are also available. [2] Phosphate is primary excreted in the urine, at the distal renal tubule. [3]
Sodium dihydrogen phosphate Sodium hydrogen phosphate Trisodium phosphate. A sodium phosphate is a generic variety of salts of sodium (Na +) and phosphate (PO 3− 4). Phosphate also forms families or condensed anions including di-, tri-, tetra-, and polyphosphates. Most of these salts are known in both anhydrous (water-free) and hydrated forms ...
Today, in its strict sense, the word pill still refers specifically to tablets (including caplets) rather than capsules (which were invented much later), but because a simple hypernym is needed to intuitively cover all such oral dosage forms, the broad sense of the word pill is also widely used and includes both tablets and capsules ...
The use of Phospho soda has been known to lead to acute phosphate nephropathy. According to the U.S. Food and Drug Administration (FDA), "Acute phosphate nephropathy is a form of acute kidney injury that is associated with deposits of calcium-phosphate crystals in the renal tubules that may result in permanent renal function impairment.
For example, see Sodium tripolyphosphate. Sometimes pyrophosphate, tripolyphosphate, tetrapolyphosphate, etc. are called diphosphate, triphosphate, tetraphosphate, etc., especially when they are part of phosphate esters in biochemistry. They are also used for scale and corrosion control by potable water providers. [6]
Sodium hypophosphite (NaPO 2 H 2, also known as sodium phosphinate) is the sodium salt of hypophosphorous acid and is often encountered as the monohydrate, NaPO 2 H 2 ·H 2 O. It is a solid at room temperature, appearing as odorless white crystals. It is soluble in water, and easily absorbs moisture from the air.
Tetrasodium pyrophosphate, also called sodium pyrophosphate, tetrasodium phosphate or TSPP, is an inorganic compound with the formula Na 4 P 2 O 7. As a salt, it is a white, water-soluble solid. It is composed of pyrophosphate anion and sodium ions. Toxicity is approximately twice that of table salt when ingested orally. [3]
Phosphate nephropathy or nephrocalcinosis [1] is an adverse renal condition that arises with a formation of phosphate crystals within the kidney's tubules. This renal insufficiency is associated with the use of oral sodium phosphate (OSP) such as C.B. Fleet's Phospho soda and Salix's Visocol, for bowel cleansing prior to a colonoscopy.