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The biology of depression is the attempt to identify a biochemical origin of depression, as opposed to theories that emphasize psychological or situational causes. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD) . [ 1 ]
A depressogen is a substance that causes or can cause depression, usually as a side effect. [1] They are the functional opposites of antidepressants. [2]Examples of drugs commonly associated with depressogenic effects include ethanol, some anticonvulsants such as the barbiturates (e.g. phenobarbital), benzodiazepines (e.g. diazepam), vigabatrin, and topiramate, corticosteroids like ...
This article needs to be updated. The reason given is: Many outdated sources and information (older than five years). Please help update this article to reflect recent events or newly available information. (July 2024) Medical condition Major depressive disorder Other names Clinical depression, major depression, unipolar depression, unipolar disorder, recurrent depression Sorrowing Old Man (At ...
Stress ulceration is a single or multiple fundic mucosal ulcers that causes upper gastrointestinal bleeding, and develops during the severe physiologic stress of serious illness. It can also cause mucosal erosions and superficial hemorrhages in patients who are critically ill, or in those who are under extreme physiologic stress, causing blood ...
The Holmes and Rahe stress scale (/ r eɪ /), [1] also known as the Social Readjustment Rating Scale, is a list of 43 stressful life events that can contribute to illness. The test works via a point accumulation score which then gives an assessment of risk.
Theories of a proposed stress–illness link suggest that both acute and chronic stress can cause illness, and studies have found such a link. [58] According to these theories, both kinds of stress can lead to changes in behavior and in physiology. Behavioral changes can involve smoking and eating habits and physical activity.
For example, in the context of depression, the diathesis-stress model can help explain why Person A may become depressed while Person B does not, even when exposed to the same stressors. [7] More recently, the diathesis-stress model has been used to explain why some individuals are more at risk for developing a disorder than others. [9]
Psychotherapy alone may not be as effective for more severe forms of depression, such as depression with a chemical imbalance in the brain. [27] Some of the main forms of psychotherapy used for the treatment of a major depressive episode, along with what makes them unique, are included below: [27] Cognitive psychotherapy: focus on patterns of ...