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Silver sulfadiazine, sold under the brand Silvadene among others, is a topical antibiotic used in partial thickness and full thickness burns to prevent infection. [1] Tentative evidence has found other antibiotics to be more effective, and therefore it is no longer generally recommended for second-degree (partial-thickness) burns, but is still ...
[75] [76] Not to treat or prevent cancer (UK, Sweden, etc.) Illegal to be marketed/advertised as a dietary supplement or medicine in the U.S. [77] Colloidal silver (a colloid consisting of silver particles suspended in liquid) and formulations containing silver salts were used by physicians in the early 20th century, but their use was largely ...
If used during pregnancy, it may increase the risk of kernicterus in the baby. [1] While the company that makes it does not recommend use during breastfeeding, use is believed to be safe if the baby is otherwise healthy. [2] It is in the sulfonamide class of medications. [1] Sulfadiazine was approved for medical use in the United States in 1941.
Sulfhemoglobinemia is usually drug induced, with drugs associated with it including sulphonamides, such as sulfasalazine or sumatriptan. Another possible cause is occupational exposure to sulfur compounds. [citation needed] It can also be caused by phenazopyridine. [3]
Induction chemotherapy is the first line treatment of cancer with a chemotherapeutic drug. This type of chemotherapy is used for curative intent. [1] [6]: 55–59 Combined modality chemotherapy is the use of drugs with other cancer treatments, such as surgery, radiation therapy, or hyperthermia therapy.
Gerhard Johannes Paul Domagk (German pronunciation: [ˈɡeːɐ̯haʁt ˈdoːmak] ⓘ; 30 October 1895 – 24 April 1964) was a German pathologist and bacteriologist.. He is credited with the discovery of sulfonamidochrysoidine (KL730) as an antibiotic for which he received the 1939 Nobel Prize in Physiology or Medicine.
For use as adjunctive therapy for second- and third-degree burns to prevent infection, adults and children should apply topically to a thickness of approximately 1.6 mm to cleaned and debrided wound once or twice per day with a sterile gloved hand. The burned area should be covered with cream at all times. [citation needed]
Busulfan was approved by the US Food and Drug Administration (FDA) for treatment of chronic myeloid leukemia (CML) in 1999. Busulfan was the mainstay of the chemotherapeutic treatment of chronic myeloid leukemia (CML) until it was displaced by the new gold standard, imatinib, though it is still in use to a degree as a result of the drug's relative low cost.