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Fexofenadine, sold under the brand name Allegra among others, [10] is an antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever and urticaria. [ 11 ] Therapeutically, fexofenadine is a selective peripheral H 1 blocker .
It contains fexofenadine, as the hydrochloride, an antihistamine; and pseudoephedrine, as the hydrochloride, a nasal decongestant. [ 2 ] In 2021, it was the 279th most commonly prescribed medication in the United States, with more than 800,000 prescriptions.
Misuse of the drug has been reported in one case at massive doses of 3,000 to 4,500 mg (100–150 × 30-mg tablets) per day, with the doses gradually increased over time by this individual. [1] [66] No fatalities due to pseudoephedrine misuse have been reported as of 2021. [17] However, death with pseudoephedrine has been reported generally.
Terfenadine acts as a peripherally-selective antihistamine, or antagonist of the histamine H 1 receptor. [3] It is a prodrug, generally completely metabolized to the active form fexofenadine in the liver by the enzyme cytochrome P450 3A4.
Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. [5] This includes allergic rhinitis (hay fever) and hives. [5] It is also available in drug combinations such as loratadine/pseudoephedrine, in which it is combined with pseudoephedrine, a nasal decongestant. [5]
Each inhalation delivers 0.4 to 0.5 mg (400 to 500 μg) in 800 mL of air. [4] [2] [5] Use is not to exceed three days. [2] Historically, it has also been used for weight loss in oral tablet preparations at a dose of 25 mg. [6] [7] No medications containing propylhexedrine are currently approved for weight loss in any country since roughly 1976. [8]
Wal-Mart v. Dukes, 564 U.S. 338 (2011), was a United States Supreme Court case in which the Court ruled that a group of roughly 1.5 million women could not be certified as a valid class of plaintiffs in a class-action lawsuit for employment discrimination against Walmart.
Depends on the tree, but potentially all of it. -- Jmabel | Talk 05:34, 23 September 2005 (UTC) [] Well, it does depend on the tree, but most "normal" trees (not, for example, palm trees) have living cells in the outer sections of their trunks (except the bark) and dead cells in the interior and the bark.
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Working to be "the most powerful patient advocate in America" - Forbes