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They are used to treat anemia due to end stage kidney disease, chemotherapy, major surgery, or certain treatments in HIV/AIDS. [1] [2] In these situations they decrease the need for blood transfusions. [2] The different agents are more or less equivalent. [2] They are given by injection. [2]
Menstrual bleeding is a common cause of iron deficiency anemia in women of childbearing age. [28] Women with menorrhagia (heavy menstrual periods) are at risk of iron deficiency anemia because they are at higher than normal risk of losing more iron during menstruation than is replaced in their diet. Most women lose about 40 mL of blood per cycle.
Studies also revealed that a transferrin saturation (serum iron concentration ÷ total iron binding capacity) over 60 percent in men and over 50 percent in women identified the presence of an abnormality in iron metabolism (hereditary hemochromatosis, heterozygotes and homozygotes) with approximately 95 percent accuracy.
Zinc and vitamin D are also essential for bone health but have the added benefit for men over 50 by reducing the risk of erectile dysfunction, a condition commonly affecting men over age 40 ...
The normal range for hemoglobin is 13.8 to 17.2 grams per deciliter (g/dL) for men and 12.1 to 15.1 g/dL for women. [6] Low hemoglobin indicates anemia but will be normal for LID. [5] Normal serum iron is between 60 and 170 micrograms per deciliter (μg/dL). [7] Normal total iron-binding capacity for both sexes is 240 to 450 μg/dL. [6]
Iron deficiency anemia is classically a microcytic, hypochromic anemia. Generally, in the UK oral preparations are trialled before using parenteral delivery, [ 20 ] unless there is the requirement for a rapid response, previous intolerance to oral iron or likely failure to respond.
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