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Encephalitis lethargica is an atypical form of encephalitis.Also known as "sleeping sickness" or "sleepy sickness" (distinct from tsetse fly–transmitted sleeping sickness), it was first described in 1917 by neurologist Constantin von Economo [2] [3] and pathologist Jean-René Cruchet. [4]
Drowsiness, yawning, disinclination for work, lack of social participation, mood changes, apathy, sleep disturbances, other fatigue-related symptoms The sopite syndrome ( / s oʊ ˈ p aɪ t / ; from Latin sopire 'to put to sleep') [ 1 ] is a neurological disorder that relates symptoms of fatigue , drowsiness , and mood changes to prolonged ...
Depressed individuals have a shorter life expectancy than those without depression, in part because people who are depressed are at risk of dying of suicide. [260] About 50% of people who die of suicide have a mood disorder such as major depression, and the risk is especially high if a person has a marked sense of hopelessness or has both ...
Sleep may not be restful, and the person may feel sluggish despite many hours of sleep, which may be a factor in the worsening of their depressive symptoms, which interfere with other aspects of their lives. [3] This type of sleep disorder may make it harder to fall and stay asleep at night than during the day.
Furthermore, it may be necessary to evaluate psychiatric diseases, such as depression or substance use disorder, as well as neurological disorders, such as narcolepsy, multiple sclerosis, and craniocervical instability. [12] [28]: 57 Finally, sleep disorders, coeliac disease, and side effects of medications may also explain symptoms. [12]
Sleep deprivation, whether total or not, can induce significant anxiety, and longer sleep deprivations tend to result in an increased level of anxiety. [83] Sleep deprivation has also shown some positive effects on mood and can be used to treat depression. [10] Chronotype can affect how sleep deprivation influences mood.
Serotonin is a neurotransmitter involved in multiple complex biological processes including aggression, pain, sleep, appetite, anxiety, depression, migraine, and vomiting. [10] In humans the effects of excess serotonin were first noted in 1960 in patients receiving an MAOI and tryptophan. [54] The syndrome is caused by increased serotonin in ...
Such illness responses include lethargy, depression, anxiety, malaise, loss of appetite, [3] [4] sleepiness, [5] hyperalgesia, [6] reduction in grooming [1] [7] and failure to concentrate. [8] Sickness behavior is a motivational state that reorganizes the organism's priorities to cope with infectious pathogens.
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