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Dogs with hemangiosarcoma rarely show clinical signs until the tumor has become very large and has metastasized. Typically, clinical signs are due to hypovolemia after the tumor ruptures, causing extensive bleeding. Owners of the affected dogs often discover that the dog has hemangiosarcoma only after the dog collapses.
The symptoms depend on the tumor's location and degree of invasion. For example, tumors in the gastrointestinal tract may cause vomiting, diarrhea, or weight loss. Tumors in the mouth may cause bad breath, difficulty swallowing, or lack of appetite. Tumors arising in the peripheral nerves may cause pain, lameness, or neurological symptoms.
The dog may also seek out warm places to lie. The symptoms of hypothyroidism are shared with many other medical conditions; it may not be the first thought when a diagnosis is made. [103] Symptoms may not appear until 75% or more of the gland is non-functional.
The survival time may be longer in large dogs, and the cure rate is 20%. If a tumor is completely removed, usually the pet will receive small doses of radiation in hopes of preventing recurrence. The survival rates are: 1 year: 59%, 3 year: 40%, 5 year: 13%.
The treatment approach depends on the site, size and symptoms present, as well as the history of hemorrhage from the lesion. [27] Microsurgery is generally preferred if the cerebral cavernous hemangioma is superficial in the central nervous system, or the risk of damage to surrounding tissue from irradiation is too high.
Illustration of venereal granulomata on a dog's penis. A canine transmissible venereal tumor (CTVT), also known as a transmissible venereal tumor (TVT), canine transmissible venereal sarcoma (CTVS), sticker tumor and infectious sarcoma, is a histiocytic tumor of the external genitalia of the dog and other canines, and is transmitted from animal to animal during mating.
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Granulomatous meningoencephalitis (GME) is an inflammatory disease of the central nervous system (CNS) of dogs and, rarely, cats.It is a form of meningoencephalitis.GME is likely second only to encephalitis caused by canine distemper virus as the most common cause of inflammatory disease of the canine CNS. [1]