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Pregabalin, sold under the brand name Lyrica among others, is an anticonvulsant, analgesic, and anxiolytic amino acid medication used to treat epilepsy, neuropathic pain, fibromyalgia, restless legs syndrome, opioid withdrawal, and generalized anxiety disorder (GAD). [13] [18] [19] Pregabalin also has antiallodynic properties.
Lyrica may cause suicidal thoughts or behavior. Call 911 or your local emergency number if you experience changes in your mood, worsening depression, or thoughts of harming yourself.
However, food has been found to substantially delay the absorption of pregabalin and to significantly reduce peak levels without affecting the bioavailability of the drug; T max values for pregabalin of 0.6 hours in a fasted state and 3.2 hours in a fed state (5-fold difference), and the C max is reduced by 25–31% in a fed versus fasted state ...
If a plan formulary does not include pregabalin or Lyrica, a person can request an exception, as drug plans can make changes to their formulary list during the year. Generic vs. brand-name drugs
In the first, Forbes et al [31] presented preliminary open-label data from five men and two women, with an average age of 68 years, who had experienced RLS symptoms for a mean of 30+ years and been treated for 10+ years using a mean of nine drugs.
In the process, metabolites, or byproducts, of the drug are produced, which can linger in our blood, urine (and even in our hair) for long after the initial effects of the drug are felt.
[32] [35] Nevertheless, benzodiazepines are still prescribed for long-term treatment of anxiety disorders, although specific antidepressants and psychological therapies are recommended as the first-line treatment options with the anticonvulsant drug pregabalin indicated as a second- or third-line treatment and suitable for long-term use. [36]
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related to: how long does pregabalin last in your body quickly for women over 65 menThe lowest prices on specific drugs - Family Circle