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Viral transformation is the change in growth, phenotype, or indefinite reproduction of cells caused by the introduction of inheritable material. Through this process, a virus causes harmful transformations of an in vivo cell or cell culture .
Nucleomics: Study of the complete set of genomic components which form "the cell nucleus as a complex, dynamic biological system, referred to as the nucleome". [ 16 ] [ 17 ] The 4D Nucleome Consortium officially joined the IHEC ( International Human Epigenome Consortium ) in 2017.
In the past nucleic acid tests have mainly been used as a secondary test to confirm positive serological results. [3] However, as they become cheaper and more automated, they are increasingly becoming the primary tool for diagnostics and can also be use for monitoring of treatment of viral infected individuals t. [3]
CBD is the home of an NIH Center for the HuBMAP Integration, Visualization & Engaging (HIVE) Initiative [15] led by Ziv Bar-Joseph and an NIH Center for Multiscale Analysis of 4D Nucleome Structure and Function by Comprehensive Multimodal Data Integration [16] led by Jian Ma.
Viral evolution is a subfield of evolutionary biology and virology concerned with the evolution of viruses. [ 1 ] [ 2 ] Viruses have short generation times, and many—in particular RNA viruses —have relatively high mutation rates (on the order of one point mutation or more per genome per round of replication).
For many viral infections, different host cell strains may have a characteristic response. Currently, there are many concerns within the research community about the validity and purity of cell strains. Contamination has risen within and among laboratories. CPEs can be used to test the purity of a certain cell line.
Rotavirus. A nucleic acid test (NAT) is a technique used to detect a particular nucleic acid sequence and thus usually to detect and identify a particular species or subspecies of organism, often a virus or bacterium that acts as a pathogen in blood, tissue, urine, etc. NATs differ from other tests in that they detect genetic materials (RNA or DNA) rather than antigens or antibodies.
Viral phylodynamics is the study of how epidemiological, immunological, and evolutionary processes act and potentially interact to shape viral phylogenies. [1] Since the term was coined in 2004, research on viral phylodynamics has focused on transmission dynamics in an effort to shed light on how these dynamics impact viral genetic variation.