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Environmentally sustainable design concepts include aspects of commercial and residential heating, ventilation and air-conditioning (HVAC) technologies. Among several considerations, one of the topics attended to is the issue of indoor air quality throughout the design and construction stages of a building's life. [citation needed]
Some mold produce mycotoxins, chemical components of their cell walls, that can pose serious health risks to humans and animals. "Toxic mold" refers to mold which produce mycotoxins, such as Stachybotrys chartarum. [7] [dubious – discuss] Exposure to high levels of mycotoxins can lead to neurological disorders and death [citation needed ...
[58] [59] [60] Mycotoxins may also contribute to cancer. Dietary exposure to the mycotoxin aflatoxin B1, commonly produced by growth of the fungus Aspergillus flavus on improperly stored ground nuts in many areas of the developing world, is known to independently (and synergistically with Hepatitis B virus) induce liver cancer. [61]
Severity of symptoms depends on the dose and type of exposure, but treatment is primarily focused on supporting bodily systems damaged by the mycotoxin. The first step in most exposure cases is to remove potentially contaminated clothing and to flush the sites of exposure thoroughly with water. [68] This prevents the victim from repeated exposure.
An air quality monitor. Human exposure to aerosols has a variety of adverse health effects. [7] Building occupants complain of symptoms such as sensory irritation of the eyes, nose, or throat; neurotoxic or general health problems; skin irritation; nonspecific hypersensitivity reactions; infectious diseases; [8] and odor and taste sensations. [9]
Aspergillus penicillioides is a species of fungus in the genus Aspergillus, and is among the most xerophilic fungi. [1]Aspergillus penicillioides is typically found in indoor air, house dust, and on substrates with low water activity, such as dried food, papers affected by foxing, and inorganic objects such as binocular lenses. [2]
Ochratoxin A has a strong affinity for the brain, especially the cerebellum (Purkinje cells), ventral mesencephalon, and hippocampal structures. [13] The affinity for the hippocampus could be relevant to the pathogenesis of Alzheimer's disease, and subchronic administration to rodents induces hippocampal neurodegeneration.
Signs and symptoms range widely. [3] There is usually a rash with superficial infection. [2] Fungal infection within the skin or under the skin may present with a lump and skin changes. [3] Pneumonia-like symptoms or meningitis may occur with a deeper or systemic infection. [2] Fungi are everywhere, but only some cause disease. [13]