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  2. Neurobiological effects of physical exercise - Wikipedia

    en.wikipedia.org/wiki/Neurobiological_effects_of...

    Neuroplasticity is the process by which neurons adapt to a disturbance over time, and most often occurs in response to repeated exposure to stimuli. [27] Aerobic exercise increases the production of neurotrophic factors [note 1] (e.g., BDNF, IGF-1, VEGF) which mediate improvements in cognitive functions and various forms of memory by promoting blood vessel formation in the brain, adult ...

  3. Brain-derived neurotrophic factor - Wikipedia

    en.wikipedia.org/wiki/Brain-derived_neurotrophic...

    Brain-derived neurotrophic factor (BDNF), or abrineurin, [5] is a protein [6] that, in humans, is encoded by the BDNF gene. [7] [8] BDNF is a member of the neurotrophin family of growth factors, which are related to the canonical nerve growth factor (NGF), a family which also includes NT-3 and NT-4/NT-5.

  4. Tropomyosin receptor kinase B - Wikipedia

    en.wikipedia.org/wiki/Tropomyosin_receptor_kinase_B

    In addition, combining the induction of adult hippocampal neurogenesis and increasing BDNF levels lead to an improved cognition, mimicking exercise benefits in AD mouse models. [23] The effect of TrkB/BDNF signalling on AD pathology has been shown to be in part mediated by an increase in δ-secretase levels, via an upregulation of the JAK2 ...

  5. rs6265 - Wikipedia

    en.wikipedia.org/wiki/Rs6265

    A number of studies have examined the role of this polymorphism in risk of neuropsychiatric disorders [1], including schizophrenia [2] and depression. [3] It is generally thought that some variants of the polymorphism lead to memory impairment and susceptibility to neuropsychiatric disorders, [4] and a 2007 meta-analysis of case-control studies found a relationship between the SNP and ...

  6. Cerebrolysin - Wikipedia

    en.wikipedia.org/wiki/Cerebrolysin

    Cerebrolysin (developmental code name FPF-1070) is an experimental mixture of enzymatically-treated peptides derived from pig brain whose constituents can include brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), nerve growth factor (NGF), and ciliary neurotrophic factor (CNTF).

  7. Neurotrophic hypothesis of depression - Wikipedia

    en.wikipedia.org/wiki/Neurotrophic_hypothesis_of...

    The neurotrophic hypothesis of depression [1] proposes that major depressive disorder (MDD) is caused, at least partly, by impaired neurotrophic support.Neurotrophic factors (also known as neurotrophins) are a family of closely related proteins which regulate the survival, development, and function of neurons in both the central and peripheral nervous systems.

  8. Neuroplasticity - Wikipedia

    en.wikipedia.org/wiki/Neuroplasticity

    Neuroplasticity, also known as neural plasticity or just plasticity, is the ability of neural networks in the brain to change through growth and reorganization. . Neuroplasticity refers to the brain's ability to reorganize and rewire its neural connections, enabling it to adapt and function in ways that differ from

  9. Houston - Wikipedia

    en.wikipedia.org/wiki/Houston

    Houston (/ ˈ h juː s t ən / ⓘ HEW-stən) is the most populous city in the U.S. state of Texas and the Southern United States.Located in Southeast Texas near Galveston Bay and the Gulf of Mexico, it is the seat of Harris County; as well as the principal city of the Greater Houston metropolitan area, the fifth-most populous metropolitan statistical area in the United States and the second ...