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That can cause dangerous side effects in the long term, which is why doctors rarely prescribe oral corticosteroids for long-term asthma treatment. Another class of oral meds is called leukotriene ...
The goal of asthmatic agents is to reduce asthma exacerbation frequencies and related hospital visits. Anti-asthmatic agents as rescue medications for acute asthma attacks include short-acting β 2-adrenergic receptor agonists (SABA), short-acting muscarinic antagonists (SAMA), systemic glucocorticoids, and magnesium sulfate.
Zafirlukast is FDA-approved for the prevention and treatment of asthma in adults and children older than 5 years old. [1] Like other leukotriene receptor antagonists, zafirlukast is thought to be useful for the long-term treatment of asthma, but it is generally less effective than inhaled glucocorticoids as monotherapy (which are the standard of care) or long-acting beta-2 agonists in ...
[2] [3] [4] It is used in the management of asthma and chronic obstructive pulmonary disease (COPD). [4] It is used by inhaling the medication into the lungs. [4] Common side effects include thrush, headache, and cough. [5] Serious side effects may include worsening asthma, anaphylaxis, seizures, and heart problems. [5]
With the exception of formoterol, LABAs are not recommended for the treatment of acute asthma exacerbations because of their slower onset of action compared to salbutamol. Their long duration of action is due to the addition of a long lipophilic side-chain that binds to an exosite on adrenergic receptors.
Later research found that the combination was no more effective for asthma than theophylline alone but produced more side effects. [9] [1] [12] [7] Combinations of theophylline, ephedrine, and phenobarbital (brand name Tedral among others) have also been widely used to treat asthma.
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