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Sodium monofluorophosphate, commonly abbreviated SMFP, is an inorganic compound with the chemical formula Na 2 PO 3 F. Typical for a salt, SMFP is odourless, colourless, and water-soluble. This salt is an ingredient in some toothpastes .
Sodium monofluorophosphate can be thought of as a slow release form of fluoride. It is less acutely toxic than NaF so probably easier to handle. Its use is probably influenced by IP and tradition, etc that are associated with specific companies.
Fluoride can be delivered by many chemical methods (sodium fluoride, stannous fluoride, amine fluoride, monofluorophosphate, and more). The anti-caries performance differences between them have been shown to have less effect than variations in behavior shown by individuals in brushing, using fluoride products and post use behavior.
The stannous ion, commonly added to toothpastes as stannous fluoride or stannous chloride, has been shown to have antibacterial effects in the mouth. Research has shown that stannous fluoride-containing toothpaste inhibits extracellular polysaccharide ( EPS ) production in a multispecies biofilm greater than sodium fluoride-containing ...
Stannous fluoride was once used under the trade name Fluoristan in the original formulation of the toothpaste brand Crest, though it was later replaced with sodium monofluorophosphate under the trade name Fluoristat. Stabilised stannous fluoride is now the active ingredient in Crest/Oral B Pro-Health brand toothpaste. Although concerns have ...
The types of fluoride added to toothpaste include: sodium fluoride, sodium monofluorophosphate (MFP), and stannous fluoride. [21] [22] As stated previously, fluoride has been proven to positively affect the remineralization process through fluorapatite-like veneer formation.
Fluoride-containing compounds, such as sodium fluoride or sodium monofluorophosphate are used in topical and systemic fluoride therapy for preventing tooth decay. They are used for water fluoridation and in many products associated with oral hygiene . [ 31 ]
Monofluorophosphate is an anion with the formula PO 3 F 2−, which is a phosphate group with one oxygen atom substituted with a fluoride atom.The charge of the ion is −2. The ion resembles sulfate in size, shape and charge, and can thus form compounds with the same structure as sulfate