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Iron overload (also known as haemochromatosis or hemochromatosis) is the abnormal and increased accumulation of total iron in the body, leading to organ damage. [1] The primary mechanism of organ damage is oxidative stress , as elevated intracellular iron levels increase free radical formation via the Fenton reaction .
African iron overload is an iron overload disorder first observed among people of African descent in Southern Africa and Central Africa. [1] It is now recognized to actually be two disorders with different causes, possibly compounding each other: [2] Dietary iron overload is one contributor to iron overloads observed in African people. Home ...
The types of food are split into five categories: [5] [6] Plenty of fruit and vegetables (at least seven portions a day). 2–3; Plenty of potatoes, bread, rice, pasta and other starchy foods. 2–3; Some milk and dairy and/or calcium fortified soy milk. 2–3; Some meat, fish, eggs and/or non-dairy sources of protein (like beans and pulses). 2–3
The term "haemochromatosis" is used by different sources in many different ways. It is often used to imply an association with the HFE gene. For many years, HFE was the only known gene associated with haemochromatosis, and the term "hereditary haemochromatosis" was used to describe haemochromatosis type 1. However, many different genetic ...
A nutrition guide is a reference that provides nutrition advice for general health, typically by dividing foods into food groups and recommending servings of each group. Nutrition guides can be presented in written or visual form, and are commonly published by government agencies, health associations and university health departments.
Juvenile hemochromatosis, also known as hemochromatosis type 2, is a rare form of hereditary hemochromatosis, which emerges in young individuals, typically between 15 and 30 years of age, but occasionally later.
30 (1): 106– 12. doi: 10.1111/j.1530-0277.2006.00002.x. PMID 16433737. Nandar and Connor HFE Gene Variants Affect Iron in the Brain The Journal of Nutrition 2011. Adams et al EASL International Consensus Conference on Haemochromatosis Journal of Hepatology 2000
Transfusional hemosiderosis is treated with a number of therapies. Venipuncture removes blood. Erythrocytapheresis filters red blood cells from the blood. Chelation therapy removes iron from the blood. [5] This involves delivering iron chelating agents such as deferoxamine, deferiprone or deferasirox. [5]