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  2. Polycystic ovary syndrome - Wikipedia

    en.wikipedia.org/wiki/Polycystic_ovary_syndrome

    Polycystic ovary syndrome, or polycystic ovarian syndrome (PCOS), is the most common endocrine disorder in women of reproductive age. [14] The syndrome is named after cysts which form on the ovaries of some women with this condition, though this is not a universal symptom, and not the underlying cause of the disorder.

  3. Spironolactone - Wikipedia

    en.wikipedia.org/wiki/Spironolactone

    Gynecomastia induced by spironolactone usually regresses after a few weeks following discontinuation of the medication. [110] However, after a sufficient duration of gynecomastia being present (e.g., one year), hyalinization and fibrosis of the tissue occurs and drug-induced gynecomastia may become irreversible. [136] [137]

  4. Yes, Experts Explain You Can Still Lose Weight If You Have PCOS

    www.aol.com/yes-experts-explain-still-lose...

    Aside from making healthy lifestyle improvements, Dr. Kumar says that PCOS is often treated with a variety of medications, including metformin, hormonal contraception, and spironolactone. You ...

  5. What I Wish I Knew Before Taking Spironolactone for My ...

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  6. Mineralocorticoid receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/Mineralocorticoid_receptor...

    However, spironolactone is metabolized to three active metabolites, which give it prolonged activity (13.8 – 16. 5 hours). Spironolactone has a long half-life and is excreted 47-51% through kidneys. Patients with chronic kidney disease therefore require close monitoring when taking the drug. Spironolactone is also eliminated through feces (35-41%

  7. Sasha Pieterse speaks candidly about PCOS causing ... - AOL

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  8. Pharmacodynamics of spironolactone - Wikipedia

    en.wikipedia.org/wiki/Pharmacodynamics_of...

    Spironolactone has been identified as an inhibitor of NRG1‐ERBB4 signaling. [142] Spironolactone has been found to act as a potent inhibitor of the pannexin 1 channel, and this action appears to be involved in its antihypertensive effects independently of MR antagonism. [143] Spironolactone has been found to block hERG channels. [144]

  9. Hyperandrogenism - Wikipedia

    en.wikipedia.org/wiki/Hyperandrogenism

    Hyperandrogenism is a medical condition characterized by high levels of androgens.It is more common in women than men. [4] Symptoms of hyperandrogenism may include acne, seborrhea, hair loss on the scalp, increased body or facial hair, and infrequent or absent menstruation.

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