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The Disabled-1 (Dab1) gene encodes a key regulator of Reelin signaling. Reelin is a large glycoprotein secreted by neurons of the developing brain, particularly Cajal-Retzius cells . DAB1 functions downstream of Reln in a signaling pathway that controls cell positioning in the developing brain and during adult neurogenesis .
DAB2 mRNA is expressed in normal ovarian epithelial cells but is down-regulated or absent from ovarian carcinoma cell lines. The 770-amino acid predicted protein has an overall 83% identity with the mouse p96 protein, a putative mitogen-responsive phosphoprotein; homology is strongest in the amino-terminal end of the protein in a region corresponding to the phosphotyrosine interaction domain.
Windows 7 is the successor to Windows Vista, and its version name is Windows NT 6.1, compared to Vista's NT 6.0; its naming caused some confusion when it was announced in 2008. [19] Windows president Steven Sinofsky commented that Windows 95 was the fourth version of Windows, but Windows 7 counts up from Windows NT 4.0 as it is a descendant of ...
It supports up to 16 GB of RAM and was available in both 32-bit and 64-bit versions. [14] Windows 7 Professional This edition is targeted towards enthusiasts, small-business users, and schools. [1] It includes all the features of Windows 7 Home Premium, and adds the ability to participate in a Windows Server domain. [1]
Windows 1.0, the first independent version of Microsoft Windows, released on November 20, 1985, achieved little popularity. The project was briefly codenamed "Interface Manager" before the windowing system was implemented—contrary to popular belief that it was the original name for Windows and Rowland Hanson, the head of marketing at Microsoft, convinced the company that the name Windows ...
Windows XP Professional x64 Edition is designed to use the expanded 64-bit memory address space provided by the x86-64 64-bit extensions to the x86 IA-32 architecture, [1] which was implemented by AMD as "AMD64", found in AMD's Opteron, Athlon 64 chips (and in selected Sempron processors), and implemented by Intel as "Intel 64" (formerly known ...
All 32-bit editions of Windows 10, including Home and Pro, support up to 4 GB. [291] 64-bit editions of Windows 10 Education and Pro support up to 2 TB, 64-bit editions of Windows 10 Pro for Workstations and Enterprise support up to 6 TB, while the 64-bit edition of Windows 10 Home is limited to 128 GB. [291]
With the retail release of Windows 8.1 returning to being full version software, the "Personal Use License" exemption was removed from the OEM SKU, meaning that end users building their own PCs for personal use must use the full retail variant in order to satisfy the Windows 8.1 licensing requirements. [153] Windows 8.1 with Bing is a special ...