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[1] A fourth phase of acid secretion is known as the basal state which occurs in the times between meals (interdigestive phase). The level of acid secretion during these times is regulated by body weight, individual, number of parietal cells, and time of day. Acid secretion is lowest in the morning before awakening and highest at night. [2]
The highest concentration that gastric acid reaches in the stomach is 160 mM in the canaliculi. This is about 3 million times that of arterial blood, but almost exactly isotonic with other bodily fluids. The lowest pH of the secreted acid is 0.8, [7] but the acid is diluted in the stomach lumen to a pH of between 1 and 3.
"High-fat sources of protein, like processed or red meats and fried food, can cause reflux — especially if you’re consuming large amounts late at night," Jaclyn London, M.S., R.D., C.D.N., a ...
Chyme or chymus (/ k aɪ m /; from Greek χυμός khymos, "juice" [1] [2]) is the semi-fluid mass of partly digested food that is expelled by the stomach, through the pyloric valve, into the duodenum [3] (the beginning of the small intestine). [4]
Fried foods and other foods with a lot of fat. They delay gastric emptying, which “might just make you feel fuller longer and just not feel well,” Gentile says. Spicy foods. They can worsen ...
Pancreatic juice is a liquid secreted by the pancreas, [1] which contains a number of digestive enzymes, including trypsinogen, chymotrypsinogen, elastase, carboxypeptidase, pancreatic lipase, nucleases and amylase.
Acidity in the stomach is not buffered by food at this point and thus acts to inhibit parietal (secretes acid) and G cell (secretes gastrin) activity via D cell secretion of somatostatin. The gastric phase takes 3 to 4 hours. It is stimulated by distension of the stomach, presence of food in stomach and decrease in pH. Distention activates long ...
[citation needed] Antacids contain alkaline ions that chemically neutralize stomach gastric acid, reducing damage to the stomach lining and esophagus, and relieving pain. [1] Some antacids also inhibit pepsin, an enzyme that can damage the esophagus in acid reflux. [2] [13]
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