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A 25 mg/mL concentration of progesterone oil for intramuscular injection and a 38 mg/device progesterone intrauterine device (Progestasert) have been discontinued. [ 93 ] An oral combination formulation of micronized progesterone and estradiol in oil-filled capsules (brand name Bijuva) is marketed in the United States for the treatment of ...
[64] [65] It has also been marketed in the form of 100, 200, 250, 400, and 500 mg oral tablets; 500 and 1,000 mg oral suspensions; and as a 50 mg/mL microcrystalline aqueous suspension for intramuscular injection. [66] [67] A 100 mg/mL microcrystalline aqueous suspension for intramuscular injection was previously available as well. [64]
Hydroxyprogesterone caproate (Delalutin, Makena, Makena Preservative Free) – 125 mg/mL, 250 mg/mL; Medroxyprogesterone acetate (Depo-Provera) – 400 mg/mL – approved specifically for the treatment of endometrial/renal cancer; Progesterone (Progesterone) – 50 mg/mL (25 mg/mL discontinued)
Estradiol benzoate is and has been available as an oil solution for intramuscular injection provided as vials and ampoules at concentrations of 0.167, 0.2, 0.33, 1, 1.67, 2, 5, 10, 20, and 25 mg/mL. [ 23 ] [ 31 ] [ 8 ] It is also available as a microcrystalline aqueous suspension for intramuscular injection under the brand name Agofollin Depot.
Progestogen-only injectable contraceptives (POICs) are a form of hormonal contraception and progestogen-only contraception that are administered by injection and providing long-lasting birth control. [2] [3] As opposed to combined injectable contraceptives, they contain only a progestogen without an estrogen, and include two progestin ...
Hormone levels following a single intramuscular injection of EV/NETE (5 mg/50 mg) in healthy young men. [9] Testosterone levels were maximally suppressed by about 94%, to ~30 ng/dL, when measured at day 7. [9] EV/NETE is a combination of EV, an estrogen, and NETE, a progestogen with weak androgenic activity.
Algestone acetophenide, also known more commonly as dihydroxyprogesterone acetophenide (DHPA) and sold under the brand names Perlutal and Topasel among others, is a progestin medication which is used in combination with an estrogen as a form of long-lasting injectable birth control.
A single intramuscular injection of estradiol valerate/norethisterone enanthate (5 mg/50 mg) (Mesigyna) has been found to strongly suppress testosterone levels in men. [33] Testosterone levels decreased from a baseline of ~503 ng/dL to a trough of ~30 ng/dL (a 94% decrease) which occurred at day 7 post-injection. [33]
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