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Gastrointestinal cancer refers to malignant conditions of the gastrointestinal tract (GI tract) and accessory organs of digestion, including the esophagus, stomach, biliary system, pancreas, small intestine, large intestine, rectum and anus. The symptoms relate to the organ affected and can include obstruction (leading to difficulty swallowing ...
Stomach cancer, also known as gastric cancer, is a cancer that develops from the lining of the stomach. [10] Most cases of stomach cancers are gastric carcinomas, which can be divided into a number of subtypes, including gastric adenocarcinomas. [2] Lymphomas and mesenchymal tumors may also develop in the stomach. [2]
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract. GISTs arise in the smooth muscle pacemaker interstitial cell of Cajal, or similar cells. [2] They are defined as tumors whose behavior is driven by mutations in the KIT gene (85%), [2] PDGFRA gene (10%), [2] or BRAF kinase (rare).
Hereditary gastrointestinal cancer syndromes: familial adenomatous polyposis, hereditary nonpolyposis colorectal cancer, Peutz–Jeghers syndrome Cholecystectomy , which alters the flow of bile to the small intestine, increases the risk of small intestinal adenocarcinomas, [ 10 ] and this risk declines with increasing distance from the common ...
Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the large intestine). [5] Signs and symptoms may include blood in the stool , a change in bowel movements , weight loss, abdominal pain and fatigue. [ 9 ]
anal cancer In 2020 there were approximately 19.3 million new cancer cases and 10.0 million cancer deaths world-wide; and about 14.7% of the new cases were gastrointestinal cancers. [ 2 ] Emerging findings indicate that bile acids have a carcinogenic role throughout the digestive system.
It's becoming more common for young adults to have colorectal cancer — and to find out at later stages. ... a Duke Health medical oncologist who treats gastrointestinal cancers, ...
Pancreatic cancer is among the most deadly forms of cancer globally, with one of the lowest survival rates. In 2015, pancreatic cancers of all types resulted in 411,600 deaths globally. [8] Pancreatic cancer is the fifth-most-common cause of death from cancer in the United Kingdom, [19] and the third most-common in the United States. [20]
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