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The first MR images of a human brain were obtained in 1978 by two groups of researchers at EMI Laboratories led by Ian Robert Young and Hugh Clow. [1] In 1986, Charles L. Dumoulin and Howard R. Hart at General Electric developed MR angiography, [2] and Denis Le Bihan obtained the first images and later patented diffusion MRI. [3]
Amyloid-related imaging abnormalities (ARIA) are abnormal differences seen in magnetic resonance imaging of the brain in patients with Alzheimer's disease. ARIA is associated with anti-amyloid drugs, particularly human monoclonal antibodies such as aducanumab. [1] There are two types of ARIA: ARIA-E and ARIA-H.
[1] [4] Non-resolution of MRI abnormalities has been linked with poorer outcomes. [4] The presence of brain hemorrhage and cytotoxic edema (brain edema with concomittant brain tissue damage) is also associated with a poor prognosis. [2] If PRES was caused by pre-eclampsia or eclampsia the prognosis is better than in PRES due to other causes. [1 ...
Fluid-attenuated inversion recovery (FLAIR) is a magnetic resonance imaging sequence with an inversion recovery set to null fluids. For example, it can be used in brain imaging to suppress cerebrospinal fluid (CSF) effects on the image, so as to bring out the periventricular hyperintense lesions, such as multiple sclerosis (MS) plaques. [1]
Abnormal brain connectivity has long been theorized as a fundamental cause of psychosis in schizophrenia. [21] rs-fMRI can help evaluate regional interactions at rest and whether there are altered, reduced, or hyperactive connections in psychiatric disorders like schizophrenia. During resting-state fMRI experiments, participants are instructed ...
A ring-enhancing lesion is an abnormal radiologic sign on MRI or CT scans obtained using radiocontrast. On the image, there is an area of decreased density (see radiodensity) surrounded by a bright rim from concentration of the enhancing contrast dye. This enhancement may represent breakdown of the blood-brain barrier and the development of an ...
An MRI artifact is a visual artifact (an anomaly seen during visual representation) in magnetic resonance imaging (MRI). It is a feature appearing in an image that is not present in the original object. [1] Many different artifacts can occur during MRI, some affecting the diagnostic quality, while others may be confused with pathology.
Functional magnetic resonance imaging or functional MRI (fMRI) measures brain activity by detecting changes associated with blood flow. [1] [2] This technique relies on the fact that cerebral blood flow and neuronal activation are coupled. When an area of the brain is in use, blood flow to that region also increases. [3]