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  2. Homology (biology) - Wikipedia

    en.wikipedia.org/wiki/Homology_(biology)

    Evolutionary biology explains homologous structures as retained heredity from a common ancestor after having been subjected to adaptive modifications for different purposes as the result of natural selection. The term was first applied to biology in a non-evolutionary context by the anatomist Richard Owen in 1843.

  3. Sequence homology - Wikipedia

    en.wikipedia.org/wiki/Sequence_homology

    Based on the definition of homology specified above this terminology is incorrect since sequence similarity is the observation, homology is the conclusion. [3] Sequences are either homologous or not. [3] This involves that the term "percent homology" is a misnomer. [4]

  4. Homology - Wikipedia

    en.wikipedia.org/wiki/Homology

    Homology (biology), any characteristic of biological organisms that is derived from a common ancestor Sequence homology , biological homology between DNA, RNA, or protein sequences Homologous chromosomes , chromosomes in a biological cell that pair up (synapse) during meiosis

  5. Homologous chromosome - Wikipedia

    en.wikipedia.org/wiki/Homologous_chromosome

    A pair of homologous chromosomes, or homologs, is a set of one maternal and one paternal chromosome that pair up with each other inside a cell during fertilization. Homologs have the same genes in the same loci , where they provide points along each chromosome that enable a pair of chromosomes to align correctly with each other before ...

  6. Bivalent (genetics) - Wikipedia

    en.wikipedia.org/wiki/Bivalent_(genetics)

    A bivalent. In cellular biology, a bivalent is one pair of chromosomes (homologous chromosomes) in a tetrad.A tetrad is the association of a pair of homologous chromosomes (4 sister chromatids) physically held together by at least one DNA crossover.

  7. Homologous recombination - Wikipedia

    en.wikipedia.org/wiki/Homologous_recombination

    Whether homologous recombination or NHEJ is used to repair double-strand breaks is largely determined by the phase of cell cycle. Homologous recombination repairs DNA before the cell enters mitosis (M phase). It occurs during and shortly after DNA replication, in the S and G 2 phases of the cell cycle, when sister chromatids are more easily ...

  8. Homology directed repair - Wikipedia

    en.wikipedia.org/wiki/Homology_directed_repair

    The most common form of HDR is homologous recombination. The HDR mechanism can only be used by the cell when there is a homologous piece of DNA present in the nucleus, mostly in G2 and S phase of the cell cycle. Other examples of homology-directed repair include single-strand annealing and breakage-induced replication.

  9. Synteny - Wikipedia

    en.wikipedia.org/wiki/Synteny

    Synteny (in the modern sense) between human and mouse chromosomes. Colors in the human chromosomes indicate regions homologous with parts of the mouse chromosome of the same color. For instance, sequences homologous to mouse chromosome 1 are primarily on human chromosomes 1 and 2, but also 6, 8, and 18.