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Most individuals with G6PD deficiency are asymptomatic.When it induces hemolysis, the effect is usually short-lived. [5]Most people who develop symptoms are male, due to the X-linked pattern of inheritance, but female carriers can be affected due to unfavorable lyonization or skewed X-inactivation, where random inactivation of an X-chromosome in certain cells creates a population of G6PD ...
G6PD converts G6P into 6-phosphoglucono-δ-lactone and is the rate-limiting enzyme of the pentose phosphate pathway. Thus, regulation of G6PD has downstream consequences for the activity of the rest of the pentose phosphate pathway. Glucose-6-phosphate dehydrogenase is stimulated by its substrate G6P.
People suffering from 6PGD or G6PD deficiency (or both) are at risk of hemolytic anemia in states of oxidative stress. Oxidative stress can result from infection and from chemical exposure to medication and certain foods. Broad beans, e.g., fava beans, contain high levels of vicine, divicine, convicine and isouramil, all of which are oxidants.
Various forms of torture were used by the Marcos dictatorship in the Philippines between the declaration of martial law in 1972 and the Marcos family's ouster during the People Power Revolution in 1986. These included a range of methods Philippine forces picked up during its long periods of colonial occupation under Spanish, American, and ...
The Bolo knife was the primary weapon used by the Katipunan during the Philippine Revolution. [18] It was also used by the Filipino guerrillas and bolomen during the Philippine–American War. [19] [20] the bolo serves as a symbol for the Katipunan and the Philippine Revolution, particularly the Cry of Pugad Lawin.
Various genetic studies on Filipinos have been performed, to analyze the population genetics of the various ethnic groups in the Philippines.. The results of a DNA study conducted by the National Geographic's "The Genographic Project", based on genetic testings of Filipino people by the National Geographic in 2008–2009, found that the Philippines is made up of around 53% Southeast Asia and ...
The 24-year-old cemented his legendary status after he took the top spot in the men’s floor and vault events, making him the first male athlete in the Philippines' history to win a gold medal.
This list of conflicts in the Philippines is a timeline of events that includes pre-colonial wars, Spanish–Moro conflict, Philippine revolts against Spain, battles, skirmishes, and other related items that have occurred in the Philippines' geographical area.