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Post-treatment monitoring Osteopontin (OPN) is a promising tool for monitoring praziquantel efficacy and post-treatment fibrosis regression as (OPN) expression is modulated by S. mansoni egg antigens and its levels correlate with the severity of schistosomiasis fibrosis and portal hypertension in mice and humans. Praziquantel pharmacotherapy ...
The treatment of schistosomiasis involves the use of anthelmintic medications, such as praziquantel or oxamniquine, to kill the adult worms. In addition, supportive care, such as rehydration and nutritional support, may be necessary for individuals with severe symptoms.
Schistosoma japonicum is an important parasite and one of the major infectious agents of schistosomiasis.This parasite has a very wide host range, infecting at least 31 species of wild mammals, including nine carnivores, 16 rodents, one primate (human), two insectivores and three artiodactyls and therefore it can be considered a true zoonosis.
The adult lives in the blood vessels (mesenteric veins) near the human intestine. It causes intestinal schistosomiasis (similar to S. japonicum, S. mekongi, S. guineensis, and S. intercalatum). Clinical symptoms are caused by the eggs. As the leading cause of schistosomiasis in the world, it is the most prevalent parasite in humans.
Clinical presentation of an established S. intercalatum infection can be different in the local population and non-immune tourists. The majority of infections of foreign travelers are asymptomatic and go unnoticed. [13] Chronic schistosomiasis results in granulomata forming around eggs in the mesenteric vessels. [11]
Schistosoma is a genus of trematodes, commonly known as blood flukes.They are parasitic flatworms responsible for a highly significant group of infections in humans termed schistosomiasis, which is considered by the World Health Organization to be the second-most socioeconomically devastating parasitic disease (after malaria), infecting millions worldwide.
Routes of exposure and infection include ingestion of undercooked meat, drinking infected water, fecal–oral transmission and skin absorption. Some types of helminths and protozoa are classified as intestinal parasites that cause infection—those that reside in the intestines. These infections can damage or sicken the host (humans or other ...
It is found in Africa and the Middle East. It is the major agent of schistosomiasis, the most prevalent parasitic infection in humans. [1] It is the only blood fluke that infects the urinary tract, causing urinary schistosomiasis, and is a leading cause of bladder cancer (only next to tobacco smoking). [2] [3] The diseases are caused by the eggs.