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Spinal arthritis [11] – most commonly osteoarthritis – is the inflammation of superior and inferior facet joints within the spine. This leads to the formation of Osteophytes [11] which grow around the joints. This contributes to narrowing the spinal canal and compressing the spinal cord in the corresponding region.
The inflammatory mediators of RA including cytokines, growth factors, metalloproteinases destroy articular cartilage, subchondral bone, tendons and ligaments.Destructive synovitis leads to bone erosion and causes the ligaments of the spine to become too laxed (loose), eventually resulting in cervical spinal instability (loose neck bones).
Spinal abnormalities such as flattening of the lumbar lordosis, exaggeration of the thoracic kyphosis, and hyperextension of the cervical spine lead to limited spinal motion. Hip and shoulder arthritis can occur in some people with ankylosing spondylitis, usually early in the course of the illness. Usually, the other peripheral joints start to ...
Osteoarthritis: Causes, Symptoms & Treatment. This article was reviewed by Craig Primack, MD, FACP, FAAP, MFOMA. Osteoarthritis is the most common form of arthritis, affecting more than 32.5 ...
Inflammatory arthritis can sometimes cause symptoms in parts of the body other than the joints, like the eyes, heart, or lungs. As arthritis progresses, joint damage can get worse.
In the more narrow sense, it refers to spinal osteoarthritis, the age-related degeneration of the spinal column, which is the most common cause of spondylosis. The degenerative process in osteoarthritis chiefly affects the vertebral bodies, the neural foramina and the facet joints ( facet syndrome ).
Causes may include osteoarthritis, rheumatoid arthritis, spinal tumors, trauma, Paget's disease of the bone, scoliosis, spondylolisthesis, and the genetic condition achondroplasia. [3] It can be classified by the part of the spine affected into cervical , thoracic , and lumbar stenosis . [ 2 ]
AS can occur in any part of the spine or the entire spine, often with pain localized to either buttock or the back of the thigh from the sacroiliac joint. Arthritis in the hips and shoulders may also occur. When the condition presents before the age of 18, AS is more likely to cause pain and swelling of large lower limb joints, such as the ...
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