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The choice of anticonvulsants depends on individual patient characteristics. [42] Both newer and older drugs are generally equally effective in new onset epilepsy. [42] The newer drugs tend to have fewer side effects. [42]
In addition, lamotrigine shares few side effects with other, unrelated anticonvulsants known to inhibit sodium channels, which further emphasizes its unique properties. [73] It is a triazine derivate that inhibits voltage-sensitive sodium channels, leading to stabilization of neuronal membranes.
The discovery process identifying levetiracetam's antiepileptic potential was unique because it challenged several dogmas of antiepileptic drug discovery, and thereby encountered skepticism from the epilepsy community. [10] Common side effects of levetiracetam include sleepiness, dizziness, feeling tired, and aggression. [8]
Until the anticonvulsant medication leaves your system, you’re not going to escape the common side effects. Gabapentin has a half-life of around five to seven hours and takes two days on average ...
Common side effects include tingling, feeling tired, loss of appetite, abdominal pain, weight loss, ... As is the case for all antiepileptic drugs, it is advisable ...
Tolerance to the anticonvulsant effects of clonazepam occurs in both animals and humans. In humans, tolerance to the anticonvulsant effects of clonazepam occurs frequently. [81] [82] Chronic use of benzodiazepines can lead to the development of tolerance with a decrease of benzodiazepine binding sites.
Severe side effects may include suicide and psychosis. [8] [7] Use during pregnancy may result in harm to the fetus. [9] Primidone is an anticonvulsant of the barbiturate class; [7] however, its long-term effect in raising the seizure threshold is likely due to its active metabolite, phenobarbital. [10]
Common side effects include nausea, vomiting, dizziness, drowsiness, double vision and trouble with walking. [3] Serious side effects may include anaphylaxis, liver problems, pancreatitis, suicide ideation, and an abnormal heart beat. [3] [6] While use during pregnancy may harm the baby, use may be less risky than having a seizure.
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