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Atopic dermatitis (AD), also known as atopic eczema, is a long-term type of inflammation of the skin. [2] Atopic dermatitis is also often called simply eczema but the same term is also used to refer to dermatitis, the larger group of skin conditions. [2] [5] Atopic dermatitis results in itchy, red, swollen, and cracked skin. [2]
Atopic dermatitis is a chronic dermatitis associated with a hereditary tendency to develop allergies to food and inhalant substances. [46] [47] [48] Atopic dermatitis (atopic eczema, disseminated neurodermatitis, flexural eczema, infantile eczema, prurigo diathsique)
The Eczema Area and Severity Index (EASI) is a validated tool for the measurement of severity of atopic dermatitis.It ranges from 0 (no disease) to 72 (maximal disease). [1] [2] The EASI was developed in 1998 by modifying the Psoriasis Area and Severity Index (PASI), a widely accepted scoring system for psoriasis.
The terms dermatitis and eczema are sometimes used synonymously. [1] [14] However the term eczema is often used to specifically mean atopic dermatitis (also known as atopic eczema). [15] [7] Terminology might also differ according to countries. In some languages, dermatitis and eczema mean the same thing, while in other languages dermatitis ...
"Distribution" refers to how lesions are localized. They may be confined to a single area (a patch) or may be in several places. Some distributions correlate with the means by which a given area becomes affected. For example, contact dermatitis correlates with locations where allergen has elicited an allergic immune response.
The allergic march (also called atopic march) is a medical term used to explain the natural history of atopic manifestations. The allergic march is characterized by some antibody responses to immunoglobulin E (IgE) and clinical symptoms that may appear in childhood, and continue for years or decades and often changing with age. [1]
For treating atopic dermatitis, newer (second generation) corticosteroids, such as fluticasone propionate and mometasone furoate, are more effective and safer than older ones. They are also generally safe and do not cause skin thinning when used intermittently to treat atopic dermatitis flare-ups.
Defatting is the chemical dissolving of dermal lipids, from the skin, on contact with defatting agents.This can result in water loss from the affected area and cause the whitening and drying of the skin which may result in cracking, secondary infection and chemical irritant contact dermatitis.
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