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HIV protease inhibitors fit the active site of the HIV aspartic protease and were rationally designed utilizing knowledge of the aspartyl protease's mode of action. The most promising transition state mimic was hydroxyethylamine which led to the discovery of the first protease inhibitor, saquinavir. Following that discovery, other HIV protease ...
series) is a product line of how-to and other reference books published by Dorling Kindersley (DK). The books in this series provide a basic understanding of a complex and popular topics. The term "idiot" is used as hyperbole, to reassure readers that the guides will be basic and comprehensible, even if the topics seem intimidating.
The activation and proliferation of T cells that results from immune activation provides fresh targets for HIV infection. However, direct killing by HIV alone cannot account for the observed depletion of CD4 + T cells since only 0.01–0.10% of CD4 + T cells in the blood are infected. [citation needed]
HIV is a retrovirus that primarily infects components of the human immune system such as CD4 + T cells, macrophages and dendritic cells. It directly and indirectly destroys CD4 + T cells. [88] HIV is a member of the genus Lentivirus, [89] part of the family Retroviridae. [90] Lentiviruses share many morphological and biological characteristics.
He is featured in And the Band Played On, a non-fiction book by San Francisco Chronicle journalist Randy Shilts, which chronicles the discovery and spread of HIV/AIDS. Curran was a pioneer in the field in that he was one of the first scientists to recognize the infectious nature of HIV/AIDS, and he is recognized for fighting the stigmatization ...
Inventing the AIDS Virus received a positive review from David Crowe in Natural Life, [5] mixed reviews from Tina Neville in Library Journal and Richard Horton in The New York Review of Books, [6] [7] and negative reviews from the sociologist Steven Epstein in The Washington Post, [8] the physician June E. Osborn in The New York Times Book Review, [9] and Phyllida Brown in New Scientist. [10]
Notable For Dummies books include: DOS For Dummies, the first, published in 1991, whose first printing was just 7,500 copies [4] [5] Windows for Dummies, asserted to be the best-selling computer book of all time, with more than 15 million sold [4] L'Histoire de France Pour Les Nuls, the top-selling non-English For Dummies title, with more than ...
This category is for articles on history books with HIV/AIDS as a topic. Pages in category "History books about HIV/AIDS" The following 4 pages are in this category, out of 4 total.