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Different genetic loci for autosomal recessive, autosomal dominant, and x-linked forms of hereditary spastic paraplegia have been identified. Clinically, patients present with slowly progressive distal limb weakness and lower extremity spasticity.
Spastic paraplegia type 31 is usually a pure hereditary spastic paraplegia, although a few complicated cases have been reported. The first signs and symptoms of spastic paraplegia type 31 usually appear before age 20 or after age 30.
Hereditary spastic paraplegia (HSP), also known as familial spastic paraparesis, refers to a group of inherited disorders that involves weakness and spasticity, which is stiffness of the legs. These symptoms get worse over time. Early in the disease, there may be mild trouble walking and stiffness.
Hereditary spastic paraplegia (pronounced “huh-RED-eh-ter-ee” “SPAS-ti”k “par-uh-PLEE-jee-uh”) is a group of inherited conditions that cause weakness and tightness (spasticity) in your leg muscles. Symptoms are progressive. This means they get worse over time.
G11.4 is a valid billable ICD-10 diagnosis code for Hereditary spastic paraplegia. It is found in the 2024 version of the ICD-10 Clinical Modification (CM) and can be used in all HIPAA-covered transactions from Oct 01, 2023 - Sep 30, 2024 .
Hereditary spastic paraplegia (HSP), also known as hereditary spastic paraparesis, familial spastic paraplegias, French settlement disease, or Strumpell-Lorrain disease, is a group of inherited diseases whose main feature is progressive stiffness and contraction (spasticity) in the lower limbs, as a result of damage to or dysfunction of the ...
Hereditary spastic paraplegias (HSPs) are a myriad of monogenic neurological defects aiding corticospinal and dorsal spinal cord axonal atrophy with a prevalence of 0.1–9.6 instances in every 100,000 around the world [1].