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Postganglionic sympathetic fibers innervating the cutaneous district can produce either noradrenaline or acetylcholine as neurotransmitters depending on the target structure. [10] The sympathetic cholinergic fibers connecting with the sweat glands discharge primarily by changes in deep body temperature (core temperature). [11]
Sweat glands, also known as sudoriferous or sudoriparous glands, from Latin sudor 'sweat', [6] [7] are small tubular structures of the skin that produce sweat. Sweat glands are a type of exocrine gland , which are glands that produce and secrete substances onto an epithelial surface by way of a duct .
There are two kinds of neurons involved in the transmission of any signal through the sympathetic system: pre-ganglionic and post-ganglionic. The shorter preganglionic neurons originate in the thoracolumbar division of the spinal cord specifically at T1 to L2~L3, and travel to a ganglion, often one of the paravertebral ganglia, where they synapse with a postganglionic neuron.
Sudomotor function refers to the autonomic nervous system control of sweat gland activity in response to various environmental and individual factors. Sweat production is a vital thermoregulatory mechanism used by the body to prevent heat-related illness as the evaporation of sweat is the body’s most effective method of heat reduction and the only cooling method available when the air ...
The pattern of innervation of the sweat gland—namely, the postganglionic sympathetic nerve fibers—allows clinicians and researchers to use sudomotor function testing to assess dysfunction of the autonomic nervous systems, through electrochemical skin conductance.
One of those things it activates is the sympathetic nervous system, resulting in symptoms like chills, sweating, heart palpitations, and blurred vision. Your primary care doctor can check your ...
In the sympathetic division, neurons are mostly adrenergic (that is, epinephrine and norepinephrine function as the primary neurotransmitters). Notable exceptions to this rule include the sympathetic innervation of sweat glands and arrectores pilorum muscles where the neurotransmitter at both pre and post ganglionic synapses is acetylcholine.
Very few parts of the sympathetic system use cholinergic receptors. In sweat glands the receptors are of the muscarinic type. The sympathetic nervous system also has some preganglionic nerves terminating at the chromaffin cells in the adrenal medulla, which secrete epinephrine and norepinephrine into the bloodstream.