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The length of the adult kidney is normally 10–12 cm, and the right kidney is often slightly longer than the left kidney. The adult kidney size is variable due to the correlation with body height and age; however, normograms for pediatric kidney size are available. [1]
The adult human kidney generates approximately 180 liters of filtrate a day, most of which is reabsorbed. [31] The normal range for a twenty four hour urine volume collection is 800 to 2,000 milliliters per day. [32] The process is also known as hydrostatic filtration due to the hydrostatic pressure exerted on the capillary walls.
Morphology is normal. The combined length of both kidneys is 80% or lower than a single normal kidney and the glomerular filtration rate is reduced to 30% of the normal. The number of renal lobes is reduced to five to six or occasionally as few as one or two. The number of nephrons per lobe is reduced as well.
The size of the renal pelvis plays a major role in the grading of hydronephrosis. Normally, the anteroposterior diameter of the renal pelvis is less than 4 mm in fetuses up to 32 weeks of gestational age and 7 mm afterwards. [2] In adults, 13% of the normal population have a transverse pelvic diameter of over 10 mm. [3]
The kidney function can also be assessed with medical imaging. Some forms of imaging, such as kidney ultrasound or CT scans, may assess kidney function by indicating chronic disease that can impact function, by showing a small or shrivelled kidney. [citation needed].
In adults, cutoff values for renal pelvic dilation have been defined differently by different sources, with anteroposterior diameters ranging between 10 and 20 mm. [19] About 13% of normal healthy adults have a transverse pelvic diameter of over 10 mm. [20]
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A glomerular filtration rate (GFR) ≥ 60 mL/min/1.73 m 2 is considered normal without chronic kidney disease if there is no kidney damage present. Kidney damage is defined as signs of damage seen in blood, urine, or imaging studies which include lab albumin/creatinine ratio (ACR) ≥ 30. [ 59 ]