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Fibroblasts that are acting like chondrocytes can deposit calcium into the soft tissues as they do in bone. Calcification in the tendons is a common component of tendinopathy. The calcification consists of tendinitis is caused by deposits of calcium phosphate crystals in the tendon. [ 1 ]
Calcification is the accumulation of calcium salts in a body tissue. It normally occurs in the formation of bone, but calcium can be deposited abnormally in soft tissue, [1] [2] causing it to harden. Calcifications may be classified on whether there is mineral balance or not, and the location of the calcification. [3]
Note the premature arterial calcification which is a clue that this is a renal patient. Vascular calcification contributes to an increase in morbidity. Tumoral calcinosis is a rare condition in which there is calcium deposition in the soft tissue in periarticular location, around joints , outside the joint capsule . [ 1 ]
Ectopic calcification is a pathologic deposition of calcium salts in tissues or bone growth in soft tissues. This can be a symptom of hyperphosphatemia. Formation of osseous tissue in soft tissues such as the lungs, eyes, arteries, or other organs is known as ectopic calcification, dystrophic calcification, or ectopic ossification. [1]
Calcinosis is the formation of calcium deposits in any soft tissue. [1] It is a rare condition that has many different causes. These range from infection and injury to systemic diseases like kidney failure .
The initial injury to the knee, whether resulting from macro- or repetitive microtrauma, leads to the same result: calcific ossification of the soft tissue structures surrounding the medial femoral condyle. [2] This sprain or tear in the medial collateral ligament leads to inflamation of the area.
Soft tissue connects and surrounds or supports internal organs and bones, and includes muscle, tendons, ligaments, fat, fibrous tissue, lymph and blood vessels, fasciae, and synovial membranes. [ 1 ] [ 2 ] Soft tissue is tissue in the body that is not hardened by the processes of ossification or calcification such as bones and teeth .
This complex is the major stabilizer of the medial knee. Injuries to the medial side of the knee are most commonly isolated to these ligaments. [1] [3] A thorough understanding of the anatomy and function of the medial knee structures, along with a detailed history and physical exam, are imperative to diagnosing and treating these injuries.