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Amoxicillin–clavulanic acid is a first-line treatment for many types of infections, including sinus infections, and urinary tract infections, including pyelonephritis. This is, in part, because of its efficacy against gram-negative bacteria which tend to be more difficult to control than gram-positive bacteria with chemotherapeutic antibiotics.
Antibiotic usage was reduced when antibiotics were only used for ongoing symptoms and maintained patient satisfaction at 86%. [19] In a trial involving 432 children with a URTI, amoxicillin was no more effective than placebo, even for children with more severe symptoms such as fever or shortness of breath. [20] [21]
Unlike fluticasone furoate, which is approved in children as young as two years of age when used for allergies, fluticasone propionate is only approved for children four years and older. [12] [13] Fluticasone propionate was patented in 1980, and approved for medical use in 1990. [14] It is available as a generic medication. [10]
Augmentin 250, for example, contains 250 mg of amoxicillin and 125 mg of clavulanic acid. [ 12 ] [ 27 ] An intravenous preparation has been available in the UK since 1985, [ 28 ] but no parenteral preparation is available in the US; [ citation needed ] the nearest equivalent is ampicillin/sulbactam .
Sinusitis, also known as rhinosinusitis, is an inflammation of the mucous membranes that line the sinuses resulting in symptoms that may include production of thick nasal mucus, nasal congestion, facial congestion, facial pain, facial pressure, loss of smell, or fever. [6] [7] Sinusitis is a condition that affects both children and adults.
In rare cases, Fluticasone furoate may cause more serious side effects, such as adrenal suppression, glaucoma, cataracts, or growth retardation in children. These side effects are more likely to occur with long-term, high-dose use, although they are still rare. [18] Serious side effects of Fluticasone Furoate include: hives, difficulty breathing,
Moxifloxacin is an antibiotic, used to treat bacterial infections, [4] including pneumonia, conjunctivitis, endocarditis, tuberculosis, and sinusitis. [4] [5] It can be given by mouth, by injection into a vein, and as an eye drop. [5] Common side effects include diarrhea, dizziness, and headache. [4]
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