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Chromium(III) nicotinate is an ionic substance used for chromium supplementation in some nutritional products, where it is also referred to as chromium polynicotinate. It appears in products that are referred to as a medical food used for nutritional support for conditions associated with diabetes mellitus type 2 .
Approximately 2% of Cr 3+ is absorbed through the gut as chromium(III) picolinate via unsaturated passive transport. [9] Although absorption is low, CrPic 3 absorbs more efficiently than other organic and inorganic sources (i.e. CrCl 3 and chromium nicotinate) and thus accumulate at higher concentrations in tissues.
In 2005, the U.S. Food and Drug Administration approved a Qualified Health Claim for chromium picolinate with a requirement for very specific label wording: "One small study suggests that chromium picolinate may reduce the risk of insulin resistance, and therefore possibly may reduce the risk of type 2 diabetes.
And chronic cadmium exposure can damage the kidneys, bones, and lungs, as well as raise your risk for certain types of cancer, according to the Occupational Safety and Health Administration (OSHA).
Hexavalent chromium and its compounds are toxic when inhaled or ingested. Trivalent chromium is a trace mineral that is essential to human nutrition. There is a hypothetical risk of genotoxicity in humans if large amounts of trivalent chromium were somehow able to enter living cells, but normal metabolism and cell function prevent this. [2]
The US Food and Drug Administration is planning to propose a ban on certain hair-straightening products, such as chemical relaxers and pressing products, that have been linked to health risks.
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