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  2. Halogen addition reaction - Wikipedia

    en.wikipedia.org/wiki/Halogen_addition_reaction

    A halogen addition reaction is a simple organic reaction where a halogen molecule is added to the carbon–carbon double bond of an alkene functional group. [1] The general chemical formula of the halogen addition reaction is: C=C + X 2 → X−C−C−X (X represents the halogens bromine or chlorine, and in this case, a solvent could be CH 2 ...

  3. Halogenation - Wikipedia

    en.wikipedia.org/wiki/Halogenation

    Illustrative of the bromination of an alkene is the route to the anesthetic halothane from trichloroethylene: [6] Iodination and bromination can be effected by the addition of iodine and bromine to alkenes. The reaction, which conveniently proceeds with the discharge of the color of I 2 and Br 2, is the basis of the analytical method.

  4. Addition reaction - Wikipedia

    en.wikipedia.org/wiki/Addition_reaction

    General overview of addition reactions. Top to bottom: electrophilic addition to alkene, nucleophilic addition of nucleophile to carbonyl and free-radical addition of halide to alkene. Depending on the product structure, it could promptly react further to eject a leaving group to give the addition–elimination reaction sequence.

  5. Free-radical addition - Wikipedia

    en.wikipedia.org/wiki/Free-radical_addition

    Reaction is slower with alkynes than alkenes. [3]: 750 In the paradigmatic example, hydrogen bromide radicalyzes to monatomic bromine. These bromine atoms add to an alkene at the most accessible site, to give a bromoalkyl radical, with the radical on the more substituted carbon.

  6. Syn and anti addition - Wikipedia

    en.wikipedia.org/wiki/Syn_and_anti_addition

    1,2-disubstituted Cycloalkene undergoing syn and anti addition. Syn addition is the addition of two substituents to the same side (or face) of a double bond or triple bond, resulting in a decrease in bond order but an increase in number of substituents. [3] Generally the substrate will be an alkene or alkyne.

  7. Markovnikov's rule - Wikipedia

    en.wikipedia.org/wiki/Markovnikov's_rule

    Adding the hydrogen ion to one carbon atom in the alkene creates a positive charge on the other carbon, forming a carbocation intermediate. The more substituted the carbocation, the more stable it is, due to induction and hyperconjugation. The major product of the addition reaction will be the one formed from the more stable intermediate.

  8. New HIV prevention drug could reach poorest countries ... - AOL

    www.aol.com/news/hiv-prevention-drug-could-reach...

    A new long-acting preventive HIV drug could reach the world’s poorest countries by the end of 2025 or early 2026, a global health official told Reuters on Tuesday. The ambition is to start ...

  9. N-Bromosuccinimide - Wikipedia

    en.wikipedia.org/wiki/N-Bromosuccinimide

    NBS will react with alkenes 1 in aqueous solvents to give bromohydrins 2. The preferred conditions are the portionwise addition of NBS to a solution of the alkene in 50% aqueous DMSO, DME, THF, or tert-butanol at 0 °C. [3] Formation of a bromonium ion and immediate attack by water gives strong Markovnikov addition and anti stereochemical ...