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Tizanidine was approved for medical use in the United States in 1996. [5] It is available as a generic medication. [3] In 2022, it was the 94th most commonly prescribed medication in the United States, with more than 6 million prescriptions. [7] [8]
Muscle relaxants such as tizanidine are prescribed in the treatment of tension headaches. [20] Diazepam and carisoprodol are not recommended for older adults, pregnant women, or people who have depression or for those with a history of drug or alcohol addiction. [21]
Since the release of nonbenzodiazepines, also known as z-drugs, in 1992 in response to safety concerns, individuals with insomnia and other sleep disorders have increasingly been prescribed nonbenzodiazepines (2.3% in 1993 to 13.7% of Americans in 2010), less often prescribed benzodiazepines (23.5% in 1993 to 10.8% in 2010).
Cyclobenzaprine has been found not to be inferior to tizanidine, orphenadrine, and carisoprodol in the treatment of acute lower back pain, although none have been proven to be effective for long-term use (beyond two weeks of treatment).
An off-label prescription is when a healthcare provider prescribes a drug for something it hasn’t been FDA-approved for. Carolina Rudah/Istockphoto. What Are the Benefits of Compounded Tirzepatide?
Diazepam, sold under the brand name Valium among others, is a medicine of the benzodiazepine family that acts as an anxiolytic. [15] It is used to treat a range of conditions, including anxiety, seizures, alcohol withdrawal syndrome, muscle spasms, insomnia, and restless legs syndrome. [15]
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In 2022, it was the 275th most commonly prescribed medication in the United States, with more than 800,000 prescriptions. [ 13 ] [ 14 ] Guanfacine is approved by the US FDA for monotherapy treatment of ADHD, [ 3 ] as well as being used for augmentation of stimulant medications .
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