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P11-4 is a self-assembling β-peptide. It builds a 3-D bio-matrix with binding sites for Calcium-ions serving as nucleation point for hydroxyapatite (tooth mineral) formation. The high affinity to tooth mineral is based on matching distances of Ca-ion binding sites on P11-4 and Ca spacing in the crystal lattice of hydroxyapatite.
After many years of laboratory experiments and field trials, [87] its hydroxyapatite ingredient was approved as an active anti-caries agent by the Japanese Ministry of Health in 1993, and given the name Medical Hydroxyapatite to distinguish it from other forms of hydroxyapatite used in toothpaste, such as dental abrasives.
In various studies the use of nano hydroxyapatite in toothpaste showed positive results in aiding the remineralisation of dental enamel. [32] In addition to remineralisation, in vitro studies have shown that toothpastes containing nano-hydroxyapatite have the potential to reduce biofilm formation on both tooth enamel and resin-based composite ...
Natural Hydroxyapatite Toothpaste. This toothpaste uses silica and calcium carbonate to gently clean teeth without damaging the enamel. Gonchar likes that it also has essential oils, which may ...
“It may not work but it’s cheap and easy to do and it’s way better than having a filing, if one doesn’t need it.” ... Applying hydroxyapatite or fluoride to the teeth in the form of ...
The primary mineral is hydroxyapatite, which is a crystalline calcium phosphate. [4] Enamel is formed on the tooth while the tooth develops within the jaw bone before it erupts into the mouth. Once fully formed, enamel does not contain blood vessels or nerves, and is not made of cells.
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