Search results
Results from the WOW.Com Content Network
Epithelial cells in culture grow normally as tight clusters. However, they could be induced to break cell-cell contacts and become elongated and motile after exposure to a "scatter factor" that was secreted by mesenchymal cells such as Swiss 3T3 fibroblasts. [12] This was best described by Julia Gray's group in 1987. [13]
Mesenchyme is characterized morphologically by a prominent ground substance matrix containing a loose aggregate of reticular fibers and unspecialized mesenchymal stem cells. [5] Mesenchymal cells can migrate easily (in contrast to epithelial cells, which lack mobility, are organized into closely adherent sheets, and are polarized in an apical ...
Histopathologically, FMTs consist of neoplastic connective tissue cells which have differented into cells that have microscopic appearances resembling fibroblasts and/or myofibroblasts. The fibroblastic cells are characterized as spindle-shaped cells with inconspicuous nucleoli that express vimentin , an intracellular protein typically found in ...
In conjunction with mesenchymal stem cells, mesoangioblasts can embed into dystrophic muscle fibers and provide reparative proteins such as dystrophin that replace the affected cells. [ 8 ] [ 9 ] In a 2006 study, mesoangioblast transplantation was used to ameliorate the effects of muscular dystrophy in golden retrievers with a congenital ...
Parenchyma is the tissue made up of cells and intercellular spaces that fills the interior of the body of a flatworm, which is an acoelomate. This is a spongy tissue also known as a mesenchymal tissue , in which several types of cells are lodged in their extracellular matrices .
There are three main treatment options available to treat soft tissue sarcoma in cats and dogs: surgery, radiation therapy, and chemotherapy. Surgery alone or in combination with radiation therapy are used to treat the tumor at its original location, and chemotherapy is usually used to prevent or at least slow down the process of metastasis in ...
During the epithelial–mesenchymal transition (EMT), the primary mesenchyme cells (PMCs) detach from the epithelium and become internalized mesenchyme cells that can migrate freely. [ 1 ] While the mechanisms of ingression are not fully understood, studies using the sea urchin as a model organism have begun to shed light on this developmental ...
A mastocytoma in dogs (or mast cell tumor in dogs) is a neoplasm originating from mast cells in the domestic dog, which occurs mainly in the skin and subcutis. Mastocytoma are not only extremely common in dogs, but also tend to be much more malignant in them than in other animal species.