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A liver metastasis is a malignant tumor in the liver that has spread from another organ that is affected by cancer. The liver is a common site for metastatic disease because of its rich, dual blood supply (the liver receives blood via the hepatic artery and portal vein). Metastatic tumors in the liver are 20 times more common than primary liver ...
The treatment was initially developed in the early 1970s. [1] The several types of hepatic artery treatments are based on the observation that tumor cells get nearly all their nutrients from the hepatic artery, while the normal cells of the liver get about 70-80 percent of their nutrients and 50% their oxygen supply from the portal vein, and ...
This pre-treatment causes the tumors to shrink, resulting in a larger proportion of liver tissue that is functional, with broader margins. [citation needed] Preoperative evaluation involves imaging of the liver and its metastases, for example with ultrasound, computed tomography or magnetic resonance imaging.
Patients with hepatic metastatic disease from neuroendocrine tumors, gastrointestinal stromal tumors and other sarcomas, ocular melanoma, and some "hypervascular" metastases (such as those from breast cancer or renal cell cancer) may also be candidates for bland embolization, assuming the liver is the only site of disease, or when the procedure ...
Candidates for radioembolization include patients with: Unresectable liver cancer of primary or secondary origin, such as hepatocellular carcinoma [4] and liver-metastases from a different origin (e.g. colorectal cancer, [5] breast cancer, [6] neuroendocrine cancer, [7] cholangiocarcinoma [8] or soft tissue sarcomas [9])
Liver cancer can be primary in which the cancer starts in the liver, or it can be liver metastasis, or secondary, in which the cancer spreads from elsewhere in the body to the liver. Liver metastasis is the more common of the two liver cancers. [3] Instances of liver cancer are increasing globally. [8] [9]
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RL is performed in people with liver cancer, both primary such as hepatocellular carcinoma and metastatic such as from colon adenocarcinoma.Surgical resection is considered the only curative treatment for liver cancer (other than liver transplantation for hepatocellular carcinoma) but it can only be performed in patients with sufficient remnant liver after resection (amongst other criteria).