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It originally contained sodium bromide and acetanilide, both toxic substances which were eventually removed. Its current formulation contains the pain reliever aspirin and two reactive chemicals – sodium bicarbonate and citric acid – which creates effervescence when mixed with water. Sodium bicarbonate is an antacid.
Calcium carbonate antacid tablets. An antacid is a substance which neutralizes stomach acidity and is used to relieve heartburn, indigestion, or an upset stomach. [1] Some antacids have been used in the treatment of constipation and diarrhea. [2] Marketed antacids contain salts of aluminum, calcium, magnesium, or sodium. [2]
Alkalinizing agents are drugs used to manage disorders associated with low pH. For example, they may be used to treat acidosis due to kidney failure. Used for oral or parenteral therapy, sodium bicarbonate is the commonly preferred alkalinizing agent. [1] Others include potassium citrate, calcium carbonate, sodium lactate and calcium acetate. [2]
Alka-Seltzer is a combination of sodium bicarbonate, aspirin, and anhydrous citric acid used for the relief of heartburn, acid indigestion, and stomach aches. [7] Alka-Seltzer is sold in foil packets, each containing two tablets. Prior to 1984, it was also available stacked in cylindrical glass bottles. It is available in many different flavors.
Eno was first marketed by James Crossley Eno (1827–1915). [4] Legend has it that his idea for the product arose while he was working at the pharmacy of an infirmary in Newcastle, Britain, with Dennis Embleton; Embleton often prescribed an effervescent drink made by mixing sodium bicarbonate and citric acid in water, and Eno adopted this beverage. [5]
Andrews Liver Salts was a laxative and antacid for mild stomach complaints. It was sold as a powder which is added to water and mixed, creating effervescence, before being swallowed. The powder contains sugar; an antacid, sodium bicarbonate (22.6% w/w); citric acid (to provide effervescence) (19.5% w/w); and a laxative, magnesium sulphate (17.4
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Antacids (i.e. calcium carbonate and sodium bicarbonate) are often taken to treat the immediate problem [35] H2 receptor antagonists or proton pump inhibitors are effective for the two most common causes of heartburn (e.g. gastritis and GERD) Antibiotics are used if H. pylori is present. [citation needed]
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