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Mifepristone is used in more than half of all abortions in the US. The drug was first approved for use by the US Food and Drug Administration in most cases up to 10 weeks of pregnancy in 2000.
Mifepristone was developed in 1980 and came into use in France in 1987. [16] It became available in the United States in 2000, for medication abortion, and in 2010, for Cushing's syndrome. [17] [10] [12] It is on the World Health Organization's List of Essential Medicines. [18] Mifepristone was approved in Canada in January 2017. [19] [20]
The mifepristone-misoprostol combination is, by far, the most recommended drug regimen for medical abortions, but other drug combinations are available. Misoprostol alone, without mifepristone, may be used in some circumstances for medical abortion, and has even been demonstrated to be successful in the second trimester. [37]
Plan C conducts research and publicly shares information about how people are accessing mifepristone and misoprostol abortion pills in the US. Their stated goal is to transform access to abortion in the United States by normalizing the self-directed option of abortion pills by mail and placing the ability to end an early pregnancy directly in the hands of anyone who seeks it.
Mifepristone is currently in the middle of a political tug-of-war, with some conservative states seeking to restrict or eliminate access to the abortion pill, while other states are trying to ...
A New Orleans federal appeals court has rejected ideologue Texas Federal Judge Matthew Kacsmaryk’s ruling against the Food and Drug Administration’s 2000 approval of the medication abortion ...
Demand for the abortion pills mifepristone and misoprostol has grown as states have imposed bans or restrictions or seek to limit abortions after the reversal of Roe v. Wade in June 2022.
In 2000, GenBioPro's generic version of mifepristone was approved for medication abortion, as part of a two-drug regimen in combination with misoprostol. In 2023, GenBioPro sued the FDA to obtain a legal judgement confirming that mifepristone could continue to be sold, in spite of anti-abortion laws passed in some states.