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Cutaneous lymphoma, also known as lymphoma cutis, is when lymphoma involves the skin. [1] It is characterized by a proliferation of lymphoid tissue. [2] There are two main classes of lymphomas that affect the skin: [citation needed] Cutaneous T-cell lymphoma; Cutaneous B-cell lymphoma
Occurs in older adults, usually involves lymph nodes, bone marrow and spleen, associated with t(14;18) translocation overexpressing Bcl-2, indolent. Primary cutaneous follicle center lymphoma; Mantle cell lymphoma; About 3–4% of lymphomas in adults Lymphocytes of small to intermediate size growing in diffuse pattern CD5 About 50 [35] to 70% [35]
DIagram showing where lymphoma can spread in the body. Date: 30 July 2014 (released by CRUK) Source: Original email from CRUK: Author: Cancer Research UK: Permission (Reusing this file) This image has been released as part of an open knowledge project by Cancer Research UK. If re-used, attribute to Cancer Research UK / Wikimedia Commons
Micrograph showing Hodgkin's lymphoma, a type of B cell lymphoma that is usually considered separate from other B cell lymphomas. Field stain. CT scan of primary B cell lymphoma in the left ilium, as diffuse cortical and trabecular thickening of the hemipelvis, mimicking Paget's disease. [2] There are numerous kinds of lymphomas involving B cells.
The use of rituximab has been established for the treatment of B-cell–derived hematologic malignancies, including follicular lymphoma (FL) and diffuse large B-cell lymphoma (DLBCL). [ 7 ] In addition to cure-directed treatment, people can benefit from self-care to manage symptoms.
Research from Sweden has found a link between getting a tattoo of any size and an overall 21% higher risk of developing lymphoma, a type of blood cancer. Tattoos may increase blood cancer risk by ...
Examples of such signs and symptoms include splenomegaly, abdominal pain and skin rash. Other common symptoms are fever, night sweat and unexplained weight loss. [2] These symptoms are collectively called B symptoms. Mature T-cell lymphoma is fast-growing and patients are usually diagnosed at later stage.
In situ follicular lymphoma is an accumulation of monoclonal B cells (i.e. cells descendent from a single ancestral cell) in the germinal centers of lymphoid tissue. These cells commonly bear a pathological genomic abnormality, i.e. a translocation between position 32 on the long (i.e. "q") arm of chromosome 14 and position 21 on chromosome 18's q arm.