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Dennis Joseph Slamon (born August 6, 1948), [1] [2] is an American oncologist and chief of the division of Hematology-Oncology at UCLA.He is best known for his work identifying the HER2/neu oncogene that is amplified in 25–33% of breast cancer patients and the resulting treatment trastuzumab.
ERBB is abbreviated from erythroblastic oncogene B, a gene originally isolated from the avian genome. The human protein is also frequently referred to as HER2 (human epidermal growth factor receptor 2) or CD340 (cluster of differentiation 340). [5] [6] [7] HER2 is a member of the human epidermal growth factor receptor (HER/EGFR/ERBB) family ...
America Unearthed was an American entertainment television series and the first original series to air on the A&E Networks channel H2. [2] The show premiered on December 21, 2012, and was produced by Committee Films of Minneapolis, Minnesota. [ 3 ]
The USA Today critic wrote:"'Living Proof' knows its target audience, though, and appeals to it with an earnestness made more engaging by a string of winning performances. Connick sustains the breezy charm he has shown as an actor and musician, but also shows a decided urgency in tracing Slamon's often frustrating, sometimes desperate struggle ...
The following is a list of episodes from World Channel series America ReFramed, a production of American Documentary, Inc.. Since 2012, America ReFramed has broadcast over 120 films by independent filmmakers. [1] [2]
100124700 n/a Ensembl ENSG00000228630 n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) Chr 12: 53.96 – 53.97 Mb n/a PubMed search n/a Wikidata View/Edit Human HOTAIR (for HOX transcript antisense RNA) is a human gene located between HOXC11 and HOXC12 on chromosome 12. It is the first example of an RNA expressed on one chromosome that has been found to ...
Re-narrated Horizon episode, first aired in the UK in 1972. [4]We give you a behind-the-scenes look at the making of a nature film. Oxford Scientific Films Unit shows how it tackles such problems as filming a wood wasp laying its eggs inside trees, the hatching of a chick and the courtship rituals of the stickleback.
The full HERC2 gene is located at 15q13, encoded by 93 exons and its transcription is under the control of a CpG rich promoter.This region on chromosome 15 is susceptible to breaks during chromosomal rearrangement and there are at least 12 partial duplicates of HERC2 between 15q11–15q13.
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