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Buruli ulcer (/ b ə ˈ r uː l i /) [2] is an infectious disease characterized by the development of painless open wounds. The disease is limited to certain areas of the world, with most cases occurring in Sub-Saharan Africa and Australia.
The Global Buruli Ulcer Initiative (GBUI) is a World Health Organization (WHO) initiative to coordinate global efforts to control Buruli ulcer, [1] an infectious disease characterized by the development of painless open wounds. [2]
The bacteria can infect humans and some other animals, causing persistent open wounds called Buruli ulcer. M. ulcerans is closely related to Mycobacterium marinum , from which it evolved around one million years ago, and more distantly to the mycobacteria which cause tuberculosis and leprosy .
The prevalence of Buruli ulcer is unknown. [18] The risk of mortality is low, although secondary infections can be lethal. [35] Morbidity takes the form of deformity, disability, and skin lesions, which can be prevented through early treatment with antibiotics and surgery. [35] It is found in Africa, Asia, Australia, [36] and Latin America. [37]
Buruli ulcer is an infectious disease characterized by the development of painless open wounds. The disease largely occurs in sub-Saharan Africa and Australia, generally in rural areas near slow-moving or stagnant water. The first sign of infection is a small painless nodule or area of swelling, typically on the arms or legs.
Mycolactone is a polyketide-derived macrolide produced and secreted by a group of very closely related pathogenic mycobacteria species including M. ulcerans, M. liflandii (an unofficial designation), M. pseudoshottsii, and some strains of M. marinum.
In 2014, He was awarded the University of Ghana's Distinguished Award for Meritorious Service at 2014 Congregation. [22] [23] He is a fellow of the Ghana Academy of Arts and Sciences. [24] Professor Gordon Awandare has been named the first Africa Global Editor of the Experimental Biology and Medicine (EBM) journal [25]
English: A map of Africa with shading representing the number of cases of Buruli ulcer in 2018, according to the World Health Organization's Global Health Observatory data repository. Shading is in four levels: 1-150 cases - Yellow 151-300 cases - Orange 301-450 cases - Light red 451+ - Dark red (applies only to Ghana's 630 cases).