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In biochemistry, denaturation is a process in which proteins or nucleic acids lose folded structure present in their native state due to various factors, including application of some external stress or compound, such as a strong acid or base, a concentrated inorganic salt, an organic solvent (e.g., alcohol or chloroform), agitation and radiation, or heat. [3]
The most famous example is the hyperchromicity of DNA that occurs when the DNA duplex is denatured. [1] The UV absorption is increased when the two single DNA strands are being separated, either by heat or by addition of denaturant or by increasing the pH level. The opposite, a decrease of absorbance is called hypochromicity.
For an example, see Ice § Phases. Liquid: A mostly non-compressible fluid. Able to conform to the shape of its container but retains a (nearly) constant volume independent of pressure. Gas: A compressible fluid. Not only will a gas take the shape of its container but it will also expand to fill the container.
Denaturation (biochemistry), a structural change in macromolecules caused by extreme conditions; Denaturation (fissile materials), transforming fissile materials so that they cannot be used in nuclear weapons; Denaturation (food), intentional adulteration of food or drink rendering it unfit for consumption while remaining suitable for other uses
The concentration of such particulate matter and chemical residual will highest immediately after cleaning, and will decrease over time depending upon levels of contaminants, air exchange rate, and other sources of chemical residual. [5] Of most concern are the family of chemicals called VOCs such as formaldehyde, toluene, and limonene. [7]
A chaotropic agent is a molecule in water solution that can disrupt the hydrogen bonding network between water molecules (i.e. exerts chaotropic activity).This has an effect on the stability of the native state of other molecules in the solution, mainly macromolecules (proteins, nucleic acids) by weakening the hydrophobic effect.
The Psychopathology of Everyday Life. Everyday life is a key concept in cultural studies and is a specialized subject in the field of sociology.Some argue that, motivated by capitalism and industrialism's degrading effects on human existence and perception, writers and artists of the 19th century turned more towards self-reflection and the portrayal of everyday life represented in their ...
Chemistry is the scientific study of the properties and behavior of matter. [1] It is a physical science within the natural sciences that studies the chemical elements that make up matter and compounds made of atoms, molecules and ions: their composition, structure, properties, behavior and the changes they undergo during reactions with other substances.