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In biological systems, ascorbic acid can be found only at low pH, ... Vitamin C functions as a cofactor for the following enzymes: [8] Three groups of enzymes ...
Vitamin B 12 ; Vitamin C (ascorbic acid and ascorbates) Vitamin D (calciferols) Vitamin E (tocopherols and tocotrienols) Vitamin K (phylloquinones, menaquinones, and menadiones) Some sources include a fourteenth, choline. [6] Vitamins have diverse biochemical functions. Vitamin A acts as a regulator of cell and tissue growth and differentiation.
Vitamin A ; Vitamin B. Vitamin B 1 ; Vitamin B 2 ; Vitamin B 3 (niacin or nicotinic acid) Vitamin B 4 ; Vitamin B 5 (pantothenic acid) Vitamin B 6 (pyridoxine or pyridoxamine) Vitamin B 12 ; Vitamin C (ascorbic acid) Vitamin D ; Vitamin E ; Vitamin F; Vitamin H ; Vitamin K (naphthoquinone) Vitamin M
The mutant mice, like humans, entirely depend on dietary vitamin C, and they show changes indicating that the integrity of their vasculature is compromised. [19] GULO –/– mice have been used as a human model in multiple subsequent studies. [20] There have been successful attempts to activate lost enzymatic function in different animal species.
Vitamins can serve as precursors to many organic cofactors (e.g., vitamins B 1, B 2, B 6, B 12, niacin, folic acid) or as coenzymes themselves (e.g., vitamin C). However, vitamins do have other functions in the body. [29] Many organic cofactors also contain a nucleotide, such as the electron carriers NAD and FAD, and coenzyme A, which carries ...
Deficiency of vitamin C causes scurvy, formerly a major disease of sailors in long sea voyages. It is used as a food additive and a dietary supplement for its antioxidant properties. The "d" form (erythorbic acid) can be made by chemical synthesis, but has no significant biological role.
When Jaime Ross, PhD, a neuroscientist and assistant professor at the University of Rhode Island College of Pharmacy, decided to study how contaminating the drinking water of mice with tiny ...
Dehydroascorbic acid (DHA) is an oxidized form of ascorbic acid (vitamin C). It is actively imported into the endoplasmic reticulum of cells via glucose transporters. [1] It is trapped therein by reduction back to ascorbic acid by glutathione and other thiols. [2]
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