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Gametogenesis is a biological process by which diploid or haploid precursor cells undergo cell division and differentiation to form mature haploid gametes. Depending on the biological life cycle of the organism , gametogenesis occurs by meiotic division of diploid gametocytes into various gametes, or by mitosis.
In vitro studies permit a species-specific, simpler, more convenient, and more detailed analysis than can be done with the whole organism. Just as studies in whole animals more and more replace human trials, so are in vitro studies replacing studies in whole animals.
Under special conditions in vitro germ cells can acquire properties similar to those of embryonic stem cells (ESCs). The underlying mechanism of that change is still unknown. These changed cells are then called embryonic germ cells. Both cell types are pluripotent in vitro, but only ESCs have proven pluripotency in vivo. Recent studies have ...
Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery.It includes preclinical research on microorganisms and animals, filing for regulatory status, such as via the United States Food and Drug Administration for an investigational new drug to initiate clinical trials on humans, and may ...
CX-516 was the first ampakine compound developed by Cortex and while it showed good in vitro activity and positive results in animal tests, the human trials proved disappointing due mainly to low potency and short half-life.
Human blastocyst-stage biopsy for PGD is performed by making a hole in the ZP on day three of in vitro culture. This allows the developing TE to protrude after blastulation, facilitating the biopsy. This allows the developing TE to protrude after blastulation, facilitating the biopsy.
Advances in fertility technology like egg freezing and in-vitro fertilization have made pregnancy in your 40s and 50s even more possible. Just ask these women. This Mother Had A Baby At 50 Without ...
The United States Food and Drug Administration's Investigational New Drug (IND) program is the means by which a pharmaceutical company obtains permission to start human clinical trials and to ship an experimental drug across state lines (usually to clinical investigators) before a marketing application for the drug has been approved.